The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast
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Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeresATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylationChl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathwayRegulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatinFission yeast Rad26 responds to DNA damage independently of Rad3The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defectsProtein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase.Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection.Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage.Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication.Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress.Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks.MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae.Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair.Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint.Yeast axial-element protein, Red1, binds SUMO chains to promote meiotic interhomologue recombination and chromosome synapsis.Control of the yeast telomeric senescence survival pathways of recombination by the Mec1 and Mec3 DNA damage sensors and RPA.The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function.LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiaeHyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression.Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel SyndromeQuaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activitiesThe Dimeric Architecture of Checkpoint Kinases Mec1ATR and Tel1ATM Reveal a Common Structural OrganizationReplication protein A is sequentially phosphorylated during meiosis.Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint.Role of the C terminus of Mec1 checkpoint kinase in its localization to sites of DNA damage.Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations.ATRIP associates with replication protein A-coated ssDNA through multiple interactions.The fission yeast DNA structure checkpoint protein Rad26ATRIP/LCD1/UVSD accumulates in the cytoplasm following microtubule destabilizationThe checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint.Function of a conserved checkpoint recruitment domain in ATRIP proteins.Poetry in motion: Increased chromosomal mobility after DNA damage.A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae.Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase.Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damageFission yeast Rad26 is a regulatory subunit of the Rad3 checkpoint kinase.Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activitySuppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae.A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1.
P2860
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P2860
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast
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2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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The checkpoint protein Ddc2, f ...... osphorylation in budding yeast
@ast
The checkpoint protein Ddc2, f ...... osphorylation in budding yeast
@en
The checkpoint protein Ddc2, f ...... sphorylation in budding yeast.
@nl
type
label
The checkpoint protein Ddc2, f ...... osphorylation in budding yeast
@ast
The checkpoint protein Ddc2, f ...... osphorylation in budding yeast
@en
The checkpoint protein Ddc2, f ...... sphorylation in budding yeast.
@nl
prefLabel
The checkpoint protein Ddc2, f ...... osphorylation in budding yeast
@ast
The checkpoint protein Ddc2, f ...... osphorylation in budding yeast
@en
The checkpoint protein Ddc2, f ...... sphorylation in budding yeast.
@nl
P2093
P2860
P3181
P1433
P1476
The checkpoint protein Ddc2, f ...... osphorylation in budding yeast
@en
P2093
G Lucchini
M P Longhese
V Paciotti
P2860
P304
P3181
P407
P577
2000-08-01T00:00:00Z