Complex formation by positive and negative translational regulators of GCN4. - Wikidata - awgldk - TriplyDB

Complex formation by positive and negative translational regulators of GCN4.

Complex formation by positive and negative translational regulators of GCN4.

http://www.wikidata.org/entity/Q27936662

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Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation.Physical and functional interaction between the eukaryotic orthologs of prokaryotic translation initiation factors IF1 and IF2 Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast Coupling of cell division to cell growth by translational control of the G1 cyclin CLN3 in yeast Structural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assembly Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity Activator Gcn4 employs multiple segments of Med15/Gal11, including the KIX domain, to recruit mediator to target genes in vivo Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2 NuA4 lysine acetyltransferase Esa1 is targeted to coding regions and stimulates transcription elongation with Gcn5.eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.Complex formation by all five homologues of mammalian translation initiation factor 3 subunits from yeast Saccharomyces cerevisiae.An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4p.A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast.Isolation of a protein complex containing translation initiation factor Prt1 from Saccharomyces cerevisiae.SQT1, which encodes an essential WD domain protein of Saccharomyces cerevisiae, suppresses dominant-negative mutations of the ribosomal protein gene QSR1.Related eIF3 subunits TIF32 and HCR1 interact with an RNA recognition motif in PRT1 required for eIF3 integrity and ribosome binding.Disrupting vesicular trafficking at the endosome attenuates transcriptional activation by Gcn4.GCD11, a negative regulator of GCN4 expression, encodes the gamma subunit of eIF-2 in Saccharomyces cerevisiae Gene-specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2.Guanine nucleotide exchange factor for eukaryotic translation initiation factor 2 in Saccharomyces cerevisiae: interactions between the essential subunits GCD2, GCD6, and GCD7 and the regulatory subunit GCN3.GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.The beta subunit of eukaryotic translation initiation factor 2 binds mRNA through the lysine repeats and a region comprising the C2-C2 motif.Whi3 binds the mRNA of the G1 cyclin CLN3 to modulate cell fate in budding yeast.The Spt4p subunit of yeast DSIF stimulates association of the Paf1 complex with elongating RNA polymerase II.Nip1p associates with 40 S ribosomes and the Prt1p subunit of eukaryotic initiation factor 3 and is required for efficient translation initiation.Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5 Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2.Ribosome association of GCN2 protein kinase, a translational activator of the GCN4 gene of Saccharomyces cerevisiae.Interdependent recruitment of SAGA and Srb mediator by transcriptional activator Gcn4p.GCD2, a translational repressor of the GCN4 gene, has a general function in the initiation of protein synthesis in Saccharomyces cerevisiae.Mutations in the GCD7 subunit of yeast guanine nucleotide exchange factor eIF-2B overcome the inhibitory effects of phosphorylated eIF-2 on translation initiation.Activator Gcn4p and Cyc8p/Tup1p are interdependent for promoter occupancy at ARG1 in vivo A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)Met.GCD14p, a repressor of GCN4 translation, cooperates with Gcd10p and Lhp1p in the maturation of initiator methionyl-tRNA in Saccharomyces cerevisiae.Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2.A UV-induced mutation in neurospora that affects translational regulation in response to arginine.Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation.

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P2860

Complex formation by positive and negative translational regulators of GCN4.

http://www.wikidata.org/entity/Q27936662

description

1991 nî lūn-bûn

@nan

1991 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1991 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1991年の論文

@ja

1991年論文

@yue

1991年論文

@zh-hant

1991年論文

@zh-hk

1991年論文

@zh-mo

1991年論文

@zh-tw

1991年论文

@wuu

name

Complex formation by positive and negative translational regulators of GCN4.

@ast

Complex formation by positive and negative translational regulators of GCN4.

@en

Complex formation by positive and negative translational regulators of GCN4.

@nl

type

label

Complex formation by positive and negative translational regulators of GCN4.

@ast

Complex formation by positive and negative translational regulators of GCN4.

@en

Complex formation by positive and negative translational regulators of GCN4.

@nl

prefLabel

Complex formation by positive and negative translational regulators of GCN4.

@ast

Complex formation by positive and negative translational regulators of GCN4.

@en

Complex formation by positive and negative translational regulators of GCN4.

@nl

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Molecular and Cellular Biology

P1476

Complex formation by positive and negative translational regulators of GCN4.

@en

P2093

A G Hinnebusch

http://www.w3.org/2001/XMLSchema#string

A M Cigan

http://www.w3.org/2001/XMLSchema#string

E M Hannig

http://www.w3.org/2001/XMLSchema#string

P2860

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

Transformation of yeast

Transformation of intact yeast cells treated with alkali cations

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

"A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum

Multiple upstream AUG codons mediate translational control of GCN4.

Yeast translation initiation suppressor sui2 encodes the alpha subunit of eukaryotic initiation factor 2 and shares sequence identity with the human alpha subunit.

Molecular characterization of the yeast PRT1 gene in which mutations affect translation initiation and regulation of cell proliferation.

Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control

P304

3217-28

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scholarly article

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10.1128/MCB.11.6.3217

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6

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11

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1991-06-01T00:00:00Z

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2038327

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360174

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