Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
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Bruton's tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding proteinThe kinase Syk as an adaptor controlling sustained calcium signalling and B-cell developmentKinase activation through dimerization by human SH2-BCoordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinasesThe CBL-related protein CBLB participates in FLT3 and interleukin-7 receptor signal transduction in pro-B cellsCbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signalingFyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cellsThe Syk family of protein tyrosine kinases in T-cell activation and developmentRegulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding.Suppression of apoptosis induced by growth factor withdrawal by an oncogenic form of c-Cbl.The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.Catalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl.Adapter molecules in T cell receptor signaling.Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient miceRoles of E3 ubiquitin ligases in cell adhesion and migration.The oncogenic 70Z Cbl mutation blocks the phosphotyrosine binding domain-dependent negative regulation of ZAP-70 by c-Cbl in Jurkat T cells.c-Cbl-mediated degradation of TRAIL receptors is responsible for the development of the early phase of TRAIL resistance.Beyond the RING: CBL proteins as multivalent adapters.A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis.Akt2 inhibits the activation of NFAT in lymphocytes by modulating calcium release from intracellular storesRegulation of ZAP-70 intracellular localization: visualization with the green fluorescent protein.New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.Regulation of the mast cell response to the type 1 Fc epsilon receptor.Transmodulation of BCR signaling by transduction-incompetent antigen receptors: implications for impaired signaling in anergic B cellsSyk and pTyr'd: Signaling through the B cell antigen receptorLeukocyte Ig-like receptor B4 (LILRB4) is a potent inhibitor of FcgammaRI-mediated monocyte activation via dephosphorylation of multiple kinasesCbl family proteins: balancing FcεRI-mediated mast cell and basophil activation.Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity.Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells.SYK is upstream of phosphoinositide 3-kinase in B cell receptor signaling.Phosphorylation- and activation-independent association of the tyrosine kinase Syk and the tyrosine kinase substrates Cbl and Vav with tubulin in B-cells.Antibody cross-linking of the glycosylphosphatidylinositol-linked protein CD59 on hematopoietic cells induces signaling pathways resembling activation by complement.Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.Lipid rafts in mast cell biology.Dual regulation of T cell receptor-mediated signaling by oncogenic Cbl mutant 70Z.Activation of nuclear factor of activated T cells-(NFAT) and activating protein 1 (AP-1) by oncogenic 70Z Cbl requires an intact phosphotyrosine binding domain but not Crk(L) or p85 phosphatidylinositol 3-kinase association.Negative regulation of Fc epsilon RI-mediated degranulation by CD81.Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor.
P2860
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P2860
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
description
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1996
@ast
im November 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/11/01)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/11/01)
@nl
наукова стаття, опублікована в листопаді 1996
@uk
مقالة علمية (نشرت في نوفمبر 1996)
@ar
name
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
@ast
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
@en
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
@nl
type
label
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
@ast
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
@en
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
@nl
prefLabel
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
@ast
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
@en
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
@nl
P2093
P2860
P356
P1476
Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
@en
P2093
A. M. Scharenberg
J. A. Donovan
J. P. Kinet
L. E. Samelson
L. O. Beitz
P2860
P304
P356
10.1084/JEM.184.5.1713
P407
P577
1996-11-01T00:00:00Z