Dysregulation of cyclin dependent kinase 6 expression in splenic marginal zone lymphoma through chromosome 7q translocations
about
Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformationTDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expressionPanhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsBreakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer typesMolecular mechanism of G1 arrest and cellular senescence induced by LEE011, a novel CDK4/CDK6 inhibitor, in leukemia cells.Defining the borders of splenic marginal zone lymphoma: a multiparameter study.Genetic analysis of mammalian cyclin-dependent kinases and their inhibitors.Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis.Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6.Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8.miRNA-183 suppresses apoptosis and promotes proliferation in esophageal cancer by targeting PDCD4Cell kinetics and cell cycle regulation in lymphomas.Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation.Splenic marginal zone lymphoma with villous lymphocytes shows on-going immunoglobulin gene mutationsNovel genomic imbalances in B-cell splenic marginal zone lymphomas revealed by comparative genomic hybridization and cytogenetics.Regulation of the G1/S phase of the cell cycle and alterations in the RB pathway in human lung cancer.CDK4: A Key Player in the Cell Cycle, Development, and CancerImmunoglobulin gene translocations in chronic lymphocytic leukemia: A report of 35 patients and review of the literature.A new class of cyclin dependent kinase in Chlamydomonas is required for coupling cell size to cell division.Slit2 inhibits growth and metastasis of fibrosarcoma and squamous cell carcinomaPalbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6.Clinicopathologic features of CDK6 translocation-associated B-cell lymphoproliferative disordersDifferential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation.Cell cycle proteins as promising targets in cancer therapySplenic marginal-zone lymphoma: ontogeny and genetics.Fluorescence in situ hybridization study of chromosome 7 aberrations in hepatosplenic T-cell lymphoma: isochromosome 7q as a common abnormality accumulating in forms with features of cytologic progression.Relevance of Fusion Genes in Pediatric Cancers: Toward Precision Medicine.Genetic aberrations in small B-cell lymphomas and leukemias: molecular pathology, clinical relevance and therapeutic targets.High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma.Amplification at 7q22 targets cyclin-dependent kinase 6 in T-cell lymphoma.A narrow deletion of 7q is common to HCL, and SMZL, but not CLL.Genomic abnormalities acquired in the blastic transformation of splenic marginal zone B-cell lymphoma.Ectopic expression of Cdk6 circumvents transforming growth factor-beta mediated growth inhibition.Treatment of splenic marginal zone lymphoma of the CNS with high-dose therapy and allogeneic stem cell transplantationOverexpression of Cdk6-cyclin D3 highly sensitizes cells to physical and chemical transformation.MiR-29 silencing modulates the expression of target genes related to proliferation, apoptosis and methylation in Burkitt lymphoma cells.
P2860
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P2860
Dysregulation of cyclin dependent kinase 6 expression in splenic marginal zone lymphoma through chromosome 7q translocations
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Dysregulation of cyclin depend ...... h chromosome 7q translocations
@ast
Dysregulation of cyclin depend ...... h chromosome 7q translocations
@en
Dysregulation of cyclin depend ...... h chromosome 7q translocations
@nl
type
label
Dysregulation of cyclin depend ...... h chromosome 7q translocations
@ast
Dysregulation of cyclin depend ...... h chromosome 7q translocations
@en
Dysregulation of cyclin depend ...... h chromosome 7q translocations
@nl
prefLabel
Dysregulation of cyclin depend ...... h chromosome 7q translocations
@ast
Dysregulation of cyclin depend ...... h chromosome 7q translocations
@en
Dysregulation of cyclin depend ...... h chromosome 7q translocations
@nl
P2093
P2860
P3181
P356
P1433
P1476
Dysregulation of cyclin depend ...... h chromosome 7q translocations
@en
P2093
A P Boright
D G Oscier
J A Orchard
M M Corcoran
R E Ibbotson
R M Chapman
P2860
P2888
P304
P3181
P356
10.1038/SJ.ONC.1203033
P407
P577
1999-11-01T00:00:00Z
P5875
P6179
1005680178