Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site. - Wikidata - awgldk - TriplyDB

Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

http://www.wikidata.org/entity/Q36169197

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Mechanisms of gene duplication and amplification Chromosomal instability at common fragile sites in Seckel syndrome A fifth locus for Bardet-Biedl syndrome maps to chromosome 2q31 Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit New common variants affecting susceptibility to basal cell carcinoma Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites Adaptive evolution of pelvic reduction in sticklebacks by recurrent deletion of a Pitx1 enhancer Comparative genomics and molecular dynamics of DNA repeats in eukaryotes Molecular basis for expression of common and rare fragile sites The imprinted region on human chromosome 7q32 extends to the carboxypeptidase A gene cluster: an imprinted candidate for Silver-Russell syndrome Common fragile sites: genomic hotspots of DNA damage and carcinogenesis Dysregulation of cyclin dependent kinase 6 expression in splenic marginal zone lymphoma through chromosome 7q translocations Common fragile sites are preferential targets for HPV16 integrations in cervical tumors The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1 BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function Gene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolution 45S rDNA regions are chromosome fragile sites expressed as gaps in vitro on metaphase chromosomes of root-tip meristematic cells in Lolium spp.Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites.DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D.ATR preferentially interacts with common fragile site FRA3B and the binding requires its kinase activity in response to aphidicolin treatment.DNA breaks at fragile sites generate oncogenic RET/PTC rearrangements in human thyroid cells.Analysis of the t(3;8) of hereditary renal cell carcinoma: a palindrome-mediated translocation.Quantifying the mechanisms for segmental duplications in mammalian genomes by statistical analysis and modeling.SV40 replication in human mesothelial cells induces HGF/Met receptor activation: a model for viral-related carcinogenesis of human malignant mesothelioma.Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability.Characterization of terminal deletions at 7q32 and 22q13.3 healed by De novo telomere addition DNA instability at chromosomal fragile sites in cancer One in four individuals of African-American ancestry harbors a 5.5kb deletion at chromosome 11q13.1.Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites.Fragile sites-cytogenetic similarity with molecular diversity.Fragile site orthologs FHIT/FRA3B and Fhit/Fra14A2: evolutionarily conserved but highly recombinogenic Characterization of genetic rearrangements in esophageal squamous carcinoma cell lines by a combination of M-FISH and array-CGH: further confirmation of some split genomic regions in primary tumors.Topoisomerase II- and condensin-dependent breakage of MEC1ATR-sensitive fragile sites occurs independently of spindle tension, anaphase, or cytokinesis.Are common fragile sites merely structural domains or highly organized "functional" units susceptible to oncogenic stress?An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiae DNA topoisomerases participate in fragility of the oncogene RET.Common fragile sites are conserved features of human and mouse chromosomes and relate to large active genes.Two breakpoint clusters at fragile site FRA3B form phased nucleosomes.Global mapping of DNA conformational flexibility on Saccharomyces cerevisiae.

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Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

http://www.wikidata.org/entity/Q36169197

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Molecular characterization of ...... ian virus 40 integration site.

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PNAS.95.14.8141

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Proceedings of the National Academy of Sciences of the United States of America

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Molecular characterization of ...... mian virus 40 integration site

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A Rahat

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A Rosenthal

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B Drescher

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G Nyakatura

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H Margalit

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J R Lee

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P2860

The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers

A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition

Predicting DNA duplex stability from the base sequence

FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites

Association of a chromosome deletion syndrome with a fragile site within the proto-oncogene CBL2

Human chromosomal fragile site FRA16B is an amplified AT-rich minisatellite repeat

A human chromosome 7-specific genomic DNA library in yeast artificial chromosomes.

Magnesium ion-dependent triple-helix structure formed by homopurine-homopyrimidine sequences in supercoiled plasmid DNA.

Triplex DNA structures.

Identification of the gene FMR2, associated with FRAXE mental retardation.

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10.1073/PNAS.95.14.8141

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Matthias Platzer

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13631939

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9653154

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