Molecular organization of the complex between the muscarinic M3 receptor and the regulator of G protein signaling, Gbeta(5)-RGS7.
about
GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexesG protein beta 5 is targeted to D2-dopamine receptor-containing biochemical compartments and blocks dopamine-dependent receptor internalizationRNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signaling.Association of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons.Differential effects of the Gβ5-RGS7 complex on muscarinic M3 receptor-induced Ca2+ influx and release.cAMP regulates DEP domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membraneHelix 8 and the i3 loop of the muscarinic M3 receptor are crucial sites for its regulation by the Gβ5-RGS7 complex.β-arrestin2 plays permissive roles in the inhibitory activities of RGS9-2 on G protein-coupled receptors by maintaining RGS9-2 in the open conformation.Subcellular localization of regulator of G protein signaling RGS7 complex in neurons and transfected cells.A finer tuning of G-protein signaling through regulated control of RGS proteins.Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gαo and R7-binding Protein.RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling.Teaching an Old Drug New Tricks: Agonism, Antagonism, and Biased Signaling of Pilocarpine through M3 Muscarinic Acetylcholine Receptor.
P2860
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P2860
Molecular organization of the complex between the muscarinic M3 receptor and the regulator of G protein signaling, Gbeta(5)-RGS7.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Molecular organization of the ...... tein signaling, Gbeta(5)-RGS7.
@en
type
label
Molecular organization of the ...... tein signaling, Gbeta(5)-RGS7.
@en
prefLabel
Molecular organization of the ...... tein signaling, Gbeta(5)-RGS7.
@en
P2093
P2860
P356
P1433
P1476
Molecular organization of the ...... tein signaling, Gbeta(5)-RGS7.
@en
P2093
Konstantin Levay
Qiang Wang
Simone L Sandiford
Vladlen Z Slepak
P2860
P304
P356
10.1021/BI100080P
P407
P577
2010-06-01T00:00:00Z