TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists
about
Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesiaTRPV1 channels mediate long-term depression at synapses on hippocampal interneuronsTRPV1: a target for next generation analgesicsTRPV1: on the road to pain reliefEmerging Role of Spinal Cord TRPV1 in Pain ExacerbationThe mechanism of μ-opioid receptor (MOR)-TRPV1 crosstalk in TRPV1 activation involves morphine anti-nociception, tolerance and dependenceTRP channels and analgesiaA re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neuronsMechanisms of prolonged presynaptic Ca2+ signaling and glutamate release induced by TRPV1 activation in rat sensory neuronsFacilitation of TRPV4 by TRPV1 is required for itch transmission in some sensory neuron populationsTRPV1: A Potential Drug Target for Treating Various Diseases.Transient receptor potential (TRP) channels: a clinical perspectiveBortezomib treatment produces nocifensive behavior and changes in the expression of TRPV1, CGRP, and substance P in the rat DRG, spinal cord, and sciatic nerve.Pharmacokinetics of the TRPV1 antagonist ABT-102 in healthy human volunteers: population analysis of data from 3 phase 1 trials.Impact of central and peripheral TRPV1 and ROS levels on proinflammatory mediators and nociceptive behavior.LASSBio-881: an N-acylhydrazone transient receptor potential vanilloid subfamily type 1 antagonist orally effective against the hypernociception induced by capsaicin or partial sciatic ligationTransient receptor potential channels: targeting pain at the source.Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1.Acidosis Mediates the Switching of Gs-PKA and Gi-PKCε Dependence in Prolonged Hyperalgesia Induced by Inflammation.Mice lacking functional TRPV1 are protected from pressure overload cardiac hypertrophyPersistent Nociception Triggered by Nerve Growth Factor (NGF) Is Mediated by TRPV1 and Oxidative Mechanisms.Spinal NKCC1 blockade inhibits TRPV1-dependent referred allodyniaThermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis.Antinociception of petroleum ether fraction derived from crude methanol extract of Melastoma malabathricum leaves and its possible mechanisms of action in animal models.Unravelling the mystery of capsaicin: a tool to understand and treat painTRPV1-dependent and -independent alterations in the limbic cortex of neuropathic mice: impact on glial caspases and pain perception.TRPV1 is important for mechanical and heat sensitivity in uninjured animals and development of heat hypersensitivity after muscle inflammationUnderstanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin.The effects of intra-articular resiniferatoxin on monosodium iodoacetate-induced osteoarthritic pain in rats.Serotonin Receptor 2B Mediates Mechanical Hyperalgesia by Regulating Transient Receptor Potential Vanilloid 1Upregulation of Vanilloid Receptor-1 in Functional Dyspepsia With or Without Helicobacter pylori Infection.The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensorThe role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvantProtein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons.Modulation of transient receptor potential Vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C.TRPV1 Antagonists and Chronic Pain: Beyond Thermal PerceptionReceptor and channel heteromers as pain targets.The glutamatergic nature of TRPV1-expressing neurons in the spinal dorsal hornQuercetin ameliorates paclitaxel-induced neuropathic pain by stabilizing mast cells, and subsequently blocking PKCε-dependent activation of TRPV1.Targeting Pain-evoking Transient Receptor Potential Channels for the Treatment of Pain.
P2860
Q21128676-1F5D5037-0ABC-4B2C-A047-3CD795A3CCE3Q24644177-990D2D82-551E-48E1-8588-E3C5159BF291Q24649067-04A97AE1-EC83-4049-A793-C04BDEFE5ADAQ24650367-0EB43818-344D-40C3-AD74-D7F4C40E9AFBQ26765229-5CFB0FD3-64C5-4E9C-843D-3B9F8F2AAC4BQ26801420-793CE9A3-1CEB-48C3-ABF7-57AE9FC3E71CQ27021608-DA86AD01-24BE-4494-BBB5-2431DA496E55Q28272440-8F1098C9-27DF-457A-9E31-F08FF0E861F8Q28571331-8073B9D5-6641-4531-96E3-315181F182AAQ28816919-2C10CBF2-B477-4E9A-9F5B-847604DBFE76Q30434994-3D63E220-D443-414E-BF5C-1C280DF1749FQ33562143-174FFFB7-F0E3-4B80-B121-FB297B4A3F56Q33617012-675F7936-5BF2-4F81-93B6-7D87FD330F69Q33897649-3D3EBC47-FEE6-4E1B-A337-B82A94D47D1EQ34075112-018160B4-0C8F-4059-B8F2-A0B8949FBB11Q34078781-0ADEA351-BF1A-4CA5-84C5-25174E2DB217Q34912798-CD487454-C17A-4D1E-A4CF-BE7837F96074Q35452699-08D06150-92AC-48E2-B3C0-944ED4DFA18CQ35560825-0360270F-D1F4-415B-9DD7-9B01F8748F53Q35577699-B0638C2F-41C4-495F-8597-E34D16866800Q35675208-BE7D8532-0D33-4204-A83D-4639BDB1953EQ35906190-3F066B39-DFE0-4F23-B566-A236DDFD9594Q36197937-4E66E812-7536-4C51-B579-CE96CB8734C0Q36207122-635BF895-6DA1-4412-B8D8-97275A7500CAQ36293653-9774C655-C720-4155-8278-0B40DBBBB5CEQ36297957-DD88FA13-48D8-4C41-B012-F0332F61B34BQ36389328-A886C90E-2C46-4232-9372-6CF4BCDB63A4Q36483295-9F5BA660-C6EA-488E-B463-936FEA50AA88Q36488665-22EA68AB-BE94-46D3-9DD8-B619E72B4D10Q36853422-378F2EB7-B503-49D2-AC47-F9565E498244Q36993340-136FC366-21EB-4C54-8670-AADB4B5606A3Q37023861-BDAFDC79-89A2-4197-8D31-530C793A8E08Q37066172-B9CC88C0-5943-46EB-92C8-9B56DFFDC56AQ37094339-8B43E959-E22D-4116-868D-AFCCBC3E39E8Q37116100-1968B068-78B4-44F2-9039-7B49C9FCCC8FQ37148698-CBCAC2AD-A62C-4A80-92A0-BB3558160F44Q37148710-B468DD0D-97B2-4883-B921-B90855374E43Q37207516-DCBEA4E9-3EBB-4E4B-9486-9C68FE368082Q37254578-5F4528D9-1D43-4C22-B43A-1630C60A5A04Q37362053-A989A62E-7981-4D7E-9176-48ABAA193A9B
P2860
TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
TRPV1 receptors in the CNS pla ...... analgesia of TRPV1 antagonists
@ast
TRPV1 receptors in the CNS pla ...... analgesia of TRPV1 antagonists
@en
TRPV1 receptors in the CNS pla ...... analgesia of TRPV1 antagonists
@nl
type
label
TRPV1 receptors in the CNS pla ...... analgesia of TRPV1 antagonists
@ast
TRPV1 receptors in the CNS pla ...... analgesia of TRPV1 antagonists
@en
TRPV1 receptors in the CNS pla ...... analgesia of TRPV1 antagonists
@nl
prefLabel
TRPV1 receptors in the CNS pla ...... analgesia of TRPV1 antagonists
@ast
TRPV1 receptors in the CNS pla ...... analgesia of TRPV1 antagonists
@en
TRPV1 receptors in the CNS pla ...... analgesia of TRPV1 antagonists
@nl
P2093
P3181
P1476
TRPV1 receptors in the CNS pla ...... analgesia of TRPV1 antagonists
@en
P2093
A Gomtsyan
C R Faltynek
E K Bayburt
G Hernandez
H McDonald
P304
P3181
P356
10.1523/JNEUROSCI.1246-06.2006
P407
P577
2006-09-13T00:00:00Z