Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
about
The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysinesSCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastomaNovel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7HECT and RING finger families of E3 ubiquitin ligases at a glanceControl of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteinsCrystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligaseStructure of a Shigella effector reveals a new class of ubiquitin ligasesA Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination ActivitiesInsights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L ComplexA Dual E3 Mechanism for Rub1 Ligation to Cdc53Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificityBiochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongationStructure and function of a HECT domain ubiquitin-binding siteStructure of the HECT C-lobe of the UBR5 E3 ubiquitin ligaseCrystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactionsMechanism of ubiquitin ligation and lysine prioritization by a HECT E3Regulation of the RSP5 ubiquitin ligase by an intrinsic ubiquitin-binding siteAn expanded WW domain recognition motif revealed by the interaction between Smad7 and the E3 ubiquitin ligase Smurf2Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1Perilous journey: a tour of the ubiquitin-proteasome systemActivation of Erk by sonic hedgehog independent of canonical hedgehog signalling.HECT E3s and human disease.The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpointUSP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination.The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2)Constraint-based modeling and kinetic analysis of the Smad dependent TGF-beta signaling pathway.The ubiquitination code: a signalling problem.HPV E6, E6AP and cervical cancer.Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cellsThe HECT domain of the ubiquitin ligase Rsp5 contributes to substrate recognitionDegradation of AIMP1/p43 induced by hepatitis C virus E2 leads to upregulation of TGF-β signaling and increase in surface expression of gp96.USP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2.Signaling-mediated control of ubiquitin ligases in endocytosis.Deficiency of thioredoxin binding protein-2 (TBP-2) enhances TGF-β signaling and promotes epithelial to mesenchymal transition.Fucoidan inhibition of lung cancer in vivo and in vitro : role of the Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradationActivation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational changePeptide and small molecule inhibitors of HECT-type ubiquitin ligases
P2860
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P2860
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
@ast
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
@en
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
@nl
type
label
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
@ast
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
@en
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
@nl
prefLabel
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
@ast
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
@en
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
@nl
P2093
P3181
P1433
P1476
Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain
@en
P2093
Abiodun A Ogunjimi
Bruce T Seet
Christine Le Roy
Douglas J Briant
Frank Sicheri
Gianni M Di Guglielmo
Jeffrey L Wrana
Nadia Pece-Barbara
Peter Kavsak
Richele K Rasmussen
P304
P3181
P356
10.1016/J.MOLCEL.2005.06.028
P407
P577
2005-08-05T00:00:00Z