Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change - Wikidata - awgldk - TriplyDB

Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change

Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change

http://www.wikidata.org/entity/Q34478754

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Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4 SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1 The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2 Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships Expanding the ubiquitin code through post-translational modification Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin Activation of the E3 ubiquitin ligase Parkin.Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation Ubp2 regulates Rsp5 ubiquitination activity in vivo and in vitro.A RING to rule them all? Insights into the Map3k1 PHD motif provide a new mechanistic understanding into the diverse roles of Map3k1 The p53 circuit board The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1 Proteomic-based identification of CD4-interacting proteins in human primary macrophages Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP Ezrin ubiquitylation by the E3 ubiquitin ligase, WWP1, and consequent regulation of hepatocyte growth factor receptor activity Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.The coming of age of phosphoproteomics--from large data sets to inference of protein functions The ubiquitination code: a signalling problem.Basal cancer cell survival involves JNK2 suppression of a novel JNK1/c-Jun/Bcl-3 apoptotic network.Smurf-mediated differential proteolysis generates dynamic BMP signaling in germline stem cells during Drosophila testis development.Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets.Regulation of Arabidopsis defense responses against Spodoptera littoralis by CPK-mediated calcium signaling.Phosphorylation of VACM-1/Cul5 by protein kinase A regulates its neddylation and antiproliferative effect.

P2860

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P2860

Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change

http://www.wikidata.org/entity/Q34478754

description

2006 nî lūn-bûn

@nan

2006 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Activation of the E3 ubiquitin ...... -induced conformational change

@ast

Activation of the E3 ubiquitin ...... -induced conformational change

@en

Activation of the E3 ubiquitin ...... -induced conformational change

@nl

type

label

Activation of the E3 ubiquitin ...... -induced conformational change

@ast

Activation of the E3 ubiquitin ...... -induced conformational change

@en

Activation of the E3 ubiquitin ...... -induced conformational change

@nl

prefLabel

Activation of the E3 ubiquitin ...... -induced conformational change

@ast

Activation of the E3 ubiquitin ...... -induced conformational change

@en

Activation of the E3 ubiquitin ...... -induced conformational change

@nl

P1433

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P1476

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P356

PNAS.0510664103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Activation of the E3 ubiquitin ...... -induced conformational change

@en

P2093

Ewen Gallagher

http://www.w3.org/2001/XMLSchema#string

Min Gao

http://www.w3.org/2001/XMLSchema#string

Yun-Cai Liu

http://www.w3.org/2001/XMLSchema#string

P2860

Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions.

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain

BH3-ligand regulates access of MCL-1 to its E3 ligase

P304

1717-1722

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0510664103

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P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

103

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P50

P577

2006-01-30T00:00:00Z

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P5875

7328338

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P698

16446428

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

1413664

http://www.w3.org/2001/XMLSchema#string