Oncogene ect2 is related to regulators of small GTP-binding proteins
about
Activation of Rac1 by a Crk SH3-binding protein, DOCK180Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPasesCloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting proteinThe nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damageNucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activityCrystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4RhoG signals in parallel with Rac1 and Cdc42Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesisAn ECT2-centralspindlin complex regulates the localization and function of RhoAEct2 links the PKCiota-Par6alpha complex to Rac1 activation and cellular transformationA novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesisIdentification of a novel Rac1-interacting protein involved in membrane rufflingIrreversible repression of DNA synthesis in Fanconi anemia cells is alleviated by the product of a novel cyclin-related geneA DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulatorEct2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosisCDC42 and FGD1 cause distinct signaling and transforming activities.A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathwaysNovel kelch-like protein, KLEIP, is involved in actin assembly at cell-cell contact sites of Madin-Darby canine kidney cellsHuman ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesisMolecular biology of deregulated gene expression in transformed C3H/10T1/2 mouse embryo cell lines induced by specific insoluble carcinogenic nickel compounds.Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseControl of protein signaling using a computationally designed GTPase/GEF orthogonal pairRas superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?Structure and mutagenesis of the Dbl homology domainCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a dbl family memberA Rho exchange factor mediates fMet-Leu-Phe-induced NF-kappaB activation in human peripheral blood monocytesLeukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoAInhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent mannerPhosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoARhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domainIdentification of a mouse p21Cdc42/Rac activated kinaseOverexpression of the Rho-guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liverAutoinhibition of GEF activity in Intersectin 1 is mediated by the short SH3-DH domain linker.Cloning and characterization of a rhoGAP homolog from Dictyostelium discoideum.Novel functions of Ect2 in polar lamellipodia formation and polarity maintenance during "contractile ring-independent" cytokinesis in adherent cells.The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration.Identification and characterization of an activating TrkA deletion mutation in acute myeloid leukemia.
P2860
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P2860
Oncogene ect2 is related to regulators of small GTP-binding proteins
description
1993 nî lūn-bûn
@nan
1993 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Oncogene ect2 is related to regulators of small GTP-binding proteins
@ast
Oncogene ect2 is related to regulators of small GTP-binding proteins
@en
Oncogene ect2 is related to regulators of small GTP-binding proteins
@nl
type
label
Oncogene ect2 is related to regulators of small GTP-binding proteins
@ast
Oncogene ect2 is related to regulators of small GTP-binding proteins
@en
Oncogene ect2 is related to regulators of small GTP-binding proteins
@nl
prefLabel
Oncogene ect2 is related to regulators of small GTP-binding proteins
@ast
Oncogene ect2 is related to regulators of small GTP-binding proteins
@en
Oncogene ect2 is related to regulators of small GTP-binding proteins
@nl
P2093
P921
P356
P1433
P1476
Oncogene ect2 is related to regulators of small GTP-binding proteins
@en
P2093
P2888
P356
10.1038/362462A0
P407
P577
1993-04-01T00:00:00Z
P6179
1021657092