Structure and mutagenesis of the Dbl homology domain - Wikidata - awgldk - TriplyDB

Structure and mutagenesis of the Dbl homology domain

Structure and mutagenesis of the Dbl homology domain

http://www.wikidata.org/entity/Q27766337

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A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE.Membrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3 Oligomerization of DH domain is essential for Dbl-induced transformation Vav-2 controls NFAT-dependent transcription in B- but not T-lymphocytes Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics Intermolecular Interactions in a 44 kDa Interferon−Receptor Complex Detected by Asymmetric Reverse-Protonation and Two-Dimensional NOESY Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast Bud3 activates Cdc42 to establish a proper growth site in budding yeast.Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors Basic fibroblast growth factor stimulates activation of Rac1 through a p85 betaPIX phosphorylation-dependent pathway The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids Plekhg4 is a novel Dbl family guanine nucleotide exchange factor protein for rho family GTPases Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42 Differences in structural elements of Bcr-Abl oncoprotein isoforms in Chronic Myelogenous Leukemia.Signaling between focal adhesion kinase and trio.Interaction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells.Substrate specificity and recognition is conferred by the pleckstrin homology domain of the Dbl family guanine nucleotide exchange factor P-Rex2.Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.Modular PH and C2 domains in membrane attachment and other functions.The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding.XGef mediates early CPEB phosphorylation during Xenopus oocyte meiotic maturation.Autoinhibition mechanism of proto-Dbl.Biochemical analysis of SopE from Salmonella typhimurium, a highly efficient guanosine nucleotide exchange factor for RhoGTPases.Amino acids of the bacterial toxin SopE involved in G nucleotide exchange on Cdc42.Signaling to the Rho GTPases: networking with the DH domain.Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factors.Cla4 kinase triggers destruction of the Rac1-GEF Cdc24 during polarized growth in Ustilago maydis.Functional analysis of the Caenorhabditis elegans UNC-73B PH domain demonstrates a role in activation of the Rac GTPase in vitro and axon guidance in vivo.Function of the nucleotide exchange activity of vav1 in T cell development and activation.Automated protein fold determination using a minimal NMR constraint strategy.SAIL--stereo-array isotope labeling.Vav regulates activation of Rac but not Cdc42 during FcgammaR-mediated phagocytosis.A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death.The gene for a new brain specific RhoA exchange factor maps to the highly unstable chromosomal region 1p36.2-1p36.3.

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P2860

Structure and mutagenesis of the Dbl homology domain

http://www.wikidata.org/entity/Q27766337

description

1998 nî lūn-bûn

@nan

1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1998年の論文

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1998年学术文章

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1998年学术文章

@zh-cn

1998年学术文章

@zh-hans

1998年学术文章

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1998年学术文章

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1998年學術文章

@yue

name

Structure and mutagenesis of the Dbl homology domain

@ast

Structure and mutagenesis of the Dbl homology domain

@en

Structure and mutagenesis of the Dbl homology domain

@nl

type

label

Structure and mutagenesis of the Dbl homology domain

@ast

Structure and mutagenesis of the Dbl homology domain

@en

Structure and mutagenesis of the Dbl homology domain

@nl

prefLabel

Structure and mutagenesis of the Dbl homology domain

@ast

Structure and mutagenesis of the Dbl homology domain

@en

Structure and mutagenesis of the Dbl homology domain

@nl

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Nature structural biology

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Structure and mutagenesis of the Dbl homology domain

@en

P2093

B Aghazadeh

http://www.w3.org/2001/XMLSchema#string

G A Liu

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K Zhu

http://www.w3.org/2001/XMLSchema#string

M K Rosen

http://www.w3.org/2001/XMLSchema#string

T J Kubiseski

http://www.w3.org/2001/XMLSchema#string

T Pawson

http://www.w3.org/2001/XMLSchema#string

Y Zheng

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation

The structural basis of the activation of Ras by Sos

Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

Structure of guanine-nucleotide-exchange factor human Mss4 and identification of its Rab-interacting surface

Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from beta-spectrin

The solution structure of the pleckstrin homology domain of mouse Son-of-sevenless 1 (mSos1)

P2888

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1098-107

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scholarly article

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10.1038/4209

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12

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5

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1998-12-01T00:00:00Z

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13440637

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1027218113

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P698

9846881

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