Acrogranin, an acrosomal cysteine-rich glycoprotein, is the precursor of the growth-modulating peptides, granulins, and epithelins, and is expressed in somatic as well as male germ cells
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Structural and functional analysis of a promoter of the human granulin/epithelin geneThe growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcriptionThe zebrafish progranulin gene family and antisense transcripts.The role of progranulin in diabetes and kidney diseaseMechanisms of granulin deficiency: lessons from cellular and animal modelsStructure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activitiesCartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferationEffects of progranulin on blastocyst hatching and subsequent adhesion and outgrowth in the mouseA novel hematopoietic granulin induces proliferation of goldfish (Carassius auratus L.) macrophages.A novel interaction between perlecan protein core and progranulin: potential effects on tumor growth.IRE1a constitutes a negative feedback loop with BMP2 and acts as a novel mediator in modulating osteogenic differentiationGranulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis.Granulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix proteinBehavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementiaGEP, a local growth factor, is critical for odontogenesis and amelogenesis.Progranulin expression is upregulated after spinal contusion in mice.Progranulin: a growth factor, a novel TNFR ligand and a drug targetXBP1S, a BMP2-inducible transcription factor, accelerates endochondral bone growth by activating GEP growth factor.GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation.Correlation of granulin expression in intracranial meningiomas to clinical parameters.The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications.Exon/intron organization of the gene encoding the mouse epithelin/granulin precursor (acrogranin).Progranulin: an emerging target for FTLD therapies.AM67, a secretory component of the guinea pig sperm acrosomal matrix, is related to mouse sperm protein sp56 and the complement component 4-binding proteins.Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β.Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth.Proepithelin is an autocrine growth factor for bladder cancerADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.Roles of progranulin in sexual differentiation of the developing brain and adult neurogenesisGrowth factors as active participants in carcinogenesis: a perspective.Structure, function, and mechanism of progranulin; the brain and beyond.Progranulin and TDP-43: mechanistic links and future directions.Functional characterization and molecular mechanism exploration of three granulin epithelin precursor splice variants in biomineralization of the pearl oyster Pinctada fucata.Are progranulin levels associated with polycystic ovary syndrome and its possible metabolic effects in adolescents and young women?Expression of M6 and M7 lysin in Mytilus edulis is not restricted to sperm, but occurs also in oocytes and somatic tissue of males and females.Granulin and granulin repeats interact with the Tat.P-TEFb complex and inhibit Tat transactivation.Progranulin and its biological effects in cancer.Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.Progranulin Protects Hippocampal Neurogenesis via Suppression of Neuroinflammatory Responses Under Acute Immune Stress.The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness.
P2860
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P2860
Acrogranin, an acrosomal cysteine-rich glycoprotein, is the precursor of the growth-modulating peptides, granulins, and epithelins, and is expressed in somatic as well as male germ cells
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Acrogranin, an acrosomal cyste ...... tic as well as male germ cells
@ast
Acrogranin, an acrosomal cyste ...... tic as well as male germ cells
@en
Acrogranin, an acrosomal cyste ...... tic as well as male germ cells
@nl
type
label
Acrogranin, an acrosomal cyste ...... tic as well as male germ cells
@ast
Acrogranin, an acrosomal cyste ...... tic as well as male germ cells
@en
Acrogranin, an acrosomal cyste ...... tic as well as male germ cells
@nl
prefLabel
Acrogranin, an acrosomal cyste ...... tic as well as male germ cells
@ast
Acrogranin, an acrosomal cyste ...... tic as well as male germ cells
@en
Acrogranin, an acrosomal cyste ...... tic as well as male germ cells
@nl
P2093
P356
P1476
Acrogranin, an acrosomal cyste ...... tic as well as male germ cells
@en
P2093
G L Gerton
P304
P356
10.1002/MRD.1080340302
P407
P577
1993-03-01T00:00:00Z