The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
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Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's diseaseRecent developments in yeast agingEvolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in miceThe TOR pathway comes of ageDietary interventions to extend life span and health span based on calorie restrictionNaturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanismRapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous miceLessons from C. elegans: signaling pathways for longevitymTOR is a key modulator of ageing and age-related diseaseGenome-environment interactions that modulate aging: powerful targets for drug discoveryAging as an event of proteostasis collapseFoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and RictormTOR: from growth signal integration to cancer, diabetes and ageingMolecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.Rapamycin fed late in life extends lifespan in genetically heterogeneous miceRapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instabilityDevelopmental Drift and the Role of Wnt Signaling in AgingFinding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesReprogramming of energy metabolism as a driver of agingLive strong and prosper: the importance of skeletal muscle strength for healthy ageingBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesMYC, Metabolism, and CancerFOXO transcription factors: key regulators of cellular quality controlPhysiological control of germline developmentHIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegansdaf-31 encodes the catalytic subunit of N alpha-acetyltransferase that regulates Caenorhabditis elegans development, metabolism and adult lifespanA role for autophagy in the extension of lifespan by dietary restriction in C. elegansLifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegansRictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1Lifespan extension in a semelparous chordate occurs via developmental growth arrest just prior to meiotic entryManipulation of behavioral decline in Caenorhabditis elegans with the Rag GTPase raga-1Role of the hypothalamus in mediating protective effects of dietary restriction during agingGenome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.Cellular and molecular biology of aging endothelial cellsQuality control systems in cardiac agingThe cell biology of agingThe role of mTOR signaling in Alzheimer diseaseTOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxORapalogs and mTOR inhibitors as anti-aging therapeuticsHaploinsufficiency of akt1 prolongs the lifespan of mice
P2860
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P2860
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
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2004年学术文章
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2004年学术文章
@zh-cn
2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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name
The TOR pathway interacts with ...... ment, metabolism and life span
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The TOR pathway interacts with ...... ment, metabolism and life span
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The TOR pathway interacts with ...... ment, metabolism and life span
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The TOR pathway interacts with ...... ment, metabolism and life span
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The TOR pathway interacts with ...... ment, metabolism and life span
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The TOR pathway interacts with ...... ment, metabolism and life span
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The TOR pathway interacts with ...... ment, metabolism and life span
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The TOR pathway interacts with ...... ment, metabolism and life span
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The TOR pathway interacts with ...... ment, metabolism and life span
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P2093
P3181
P356
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The TOR pathway interacts with ...... ment, metabolism and life span
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P2093
Donald L Riddle
Kailiang Jia
P304
P3181
P356
10.1242/DEV.01255
P407
P577
2004-08-01T00:00:00Z