about
Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assemblyProtein requirements for sister telomere association in human cellsTelosome, a mammalian telomere-associated complex formed by multiple telomeric proteinsGenome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cellsThe human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activityIn vivo stoichiometry of shelterin componentsTINF2 mutations result in very short telomeres: analysis of a large cohort of patients with dyskeratosis congenita and related bone marrow failure syndromesTelomere protection by mammalian Pot1 requires interaction with Tpp1POT1 association with TRF2 regulates telomere lengthCharacterization of the DNA binding specificity of Shelterin complexesHow the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structuresTelomere dysfunction and cell survival: roles for distinct TIN2-containing complexesFinding the end: recruitment of telomerase to telomeresTIN2-tethered TPP1 recruits human telomerase to telomeres in vivoTINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenitaMultiple facets of TPP1 in telomere maintenanceA shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteinsSwitching human telomerase on and off with hPOT1 protein in vitroDNA processing is not required for ATM-mediated telomere damage response after TRF2 deletionPOT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombinationWRN loss induces switching of telomerase-independent mechanisms of telomere elongationSenescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressorTelomere Length Maintenance and Cardio-Metabolic Disease Prevention Through Exercise Training.Telomere protection by TPP1/POT1 requires tethering to TIN2POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes endIncreased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia.Telomere maintenance through spatial control of telomeric proteinsDysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.Distinct functions of POT1 at telomeres.A novel form of the telomere-associated protein TIN2 localizes to the nuclear matrixThe protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretionChemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Human telomeric proteins occupy selective interstitial sites.Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging.Ku must load directly onto the chromosome end in order to mediate its telomeric functions.Four faces of cellular senescence.Binding of TPP1 protein to TIN2 protein is required for POT1a,b protein-mediated telomere protection.Mitochondrial localization of telomeric protein TIN2 links telomere regulation to metabolic control
P2860
Q24297181-E58D230A-3BA6-4406-8764-61AE97CA3C9BQ24298475-EE3B1D36-EF52-41A3-B9A8-402C11D83460Q24298717-08FB7E3E-8E46-4966-8043-3769CBB1E09EQ24304989-CF34173F-0751-4C51-9AB0-2D0FE5B372F2Q24305322-C46914EE-9752-4B77-8CAA-45FAE603C5E3Q24306780-BE77FC85-6065-4FFF-9523-FD21B05AC498Q24312021-CAE913ED-68C4-42B9-AE4E-2C9B557C17EDQ24318921-6E90C47C-E68A-4A2E-A31B-8649BE36A4E1Q24319841-A761D64E-C9E0-4A43-BAE8-FD1E7AE96446Q24320254-B49FF97A-75E2-43EB-8C8A-8D74AF194F3DQ24323345-DC7EAB95-2DF2-484D-885C-DF4990AC543CQ24323494-7FB9B3E7-137A-4181-B630-4A7D6FCC9A1FQ24336203-B992E7D7-4496-408F-B87A-E171533C6CD1Q24606549-38A6448F-00C8-4FF1-879F-05AA133C3F79Q24606587-41AC9955-45B1-4C4B-9F28-6BB5A463DADCQ24655738-870BFAEF-6AF0-47C2-B6C7-235D29F7A65FQ26859063-0F7BC937-5113-4328-B608-708046170B67Q27649552-D6949022-9D3F-4601-9BB9-58FF0410553AQ28241841-CF34B803-CC2F-4E26-8FA5-3DD061125978Q28507823-7499C11D-B48D-4777-B29E-B8E4E651B704Q28510889-82A1DF9D-5579-49F9-AF59-873AFA2146DDQ28542061-9CA4F44A-AC2C-4C71-9999-FD3D6BF4BE52Q29615559-E825F1C2-8D84-4D3E-8349-CD118FDE9565Q30251870-AF005924-9145-499D-A303-6078D5719127Q31041280-0AD54674-7E44-41C9-9494-B3DA364B5951Q33217702-026AA409-AC8C-4E8E-AD25-22BCCB7D9514Q33247311-FB1B4D78-3681-4595-B97C-8596ED9EC1BBQ33287384-9181DB29-951F-4383-849A-2D0902EFEE62Q33303185-2FAF4F3F-3C0B-4E58-BC96-2504B9E5D65FQ33339823-93568C16-FB6B-439C-8266-A4C748A42462Q33410760-719C02F6-1472-45C2-8ACC-D5CDF28276DCQ33682203-C91817C0-32E7-4EC5-9E8B-B50076BC49FDQ33759285-F472B1AD-6503-460B-BC71-65B96E709FE2Q33814333-806EE251-A5CD-47EC-BA17-51937EAD2CAEQ33851199-E349A2AE-D32F-47A1-A876-6CB5E6FA3ACEQ33937189-BEC012C0-162F-4CD0-82F1-132F920EF690Q33996667-E853C703-9824-4848-8007-A7CDC10A71A9Q34025754-D65E93D5-9326-4B54-954E-1DDB84DFB28CQ34107187-BCFB286D-8E15-4D12-AF78-A66EBB15EF9AQ34293477-3B96DBEB-CC0C-44C3-B65D-67A34F841992
P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
TIN2 mediates functions of TRF2 at human telomeres
@ast
TIN2 mediates functions of TRF2 at human telomeres
@en
TIN2 mediates functions of TRF2 at human telomeres
@nl
type
label
TIN2 mediates functions of TRF2 at human telomeres
@ast
TIN2 mediates functions of TRF2 at human telomeres
@en
TIN2 mediates functions of TRF2 at human telomeres
@nl
prefLabel
TIN2 mediates functions of TRF2 at human telomeres
@ast
TIN2 mediates functions of TRF2 at human telomeres
@en
TIN2 mediates functions of TRF2 at human telomeres
@nl
P2093
P3181
P356
P1476
TIN2 mediates functions of TRF2 at human telomeres
@en
P2093
Albert R Davalos
Christian Beausejour
Judith Campisi
Patrick Kaminker
Sahn-ho Kim
Seok-Jin Heo
P304
P3181
P356
10.1074/JBC.M408650200
P407
P577
2004-10-15T00:00:00Z