Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia.
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Transcriptional activation of TINF2, a gene encoding the telomere-associated protein TIN2, by Sp1 and NF-κB factorsSIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes.HTLV-1 positive and negative T cells cloned from infected individuals display telomerase and telomere genes deregulation that predominate in activated but untransformed CD4+ T cells.Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.Tax impairs DNA replication forks and increases DNA breaks in specific oncogenic genome regionsAltered mRNA expression of telomere-associated genes in monoclonal gammopathy of undetermined significance and multiple myeloma.TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.Telomere dynamics and homeostasis in a transmissible cancerGene expression levels of human shelterin complex and shelterin-associated factors regulated by the topoisomerase II inhibitors doxorubicin and etoposide in human cultured cells.Emodin and DHA potently increase arsenic trioxide interferon-alpha-induced cell death of HTLV-I-transformed cells by generation of reactive oxygen species and inhibition of Akt and AP-1Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic backgroundTherapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damageMultiple Pathways Control the Reactivation of Telomerase in HTLV-I-Associated Leukemia.HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathwaysAn exact algorithm for finding cancer driver somatic genome alterations: the weighted mutually exclusive maximum set cover problem.Central role of PI3K in transcriptional activation of hTERT in HTLV-I-infected cellsRegulation of telomerase and telomeres: human tumor viruses take control.Telomeric repeat-binding factor 2: a marker for survival and anti-EGFR efficacy in oral carcinomaTelomere/telomerase interplay in virus-driven and virus-independent lymphomagenesis: pathogenic and clinical implications.Dynamics of telomeric chromatin at the crossroads of aging and cancer.Telomere dysfunction and its role in haematological cancer.Telomeric impact of conventional chemotherapy.Disruption of direct 3D telomere-TRF2 interaction through two molecularly disparate mechanisms is a hallmark of primary Hodgkin and Reed-Sternberg cells.Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions.Phosphorylation of telomeric repeat binding factor 1 (TRF1) by Akt causes telomere shortening.Telomere attrition induces a DNA double-strand break damage signal that reactivates p53 transcription in HTLV-I leukemic cells.Human T-cell lymphotrophic virus type I rex and p30 interactions govern the switch between virus latency and replication.Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection.Human T-cell leukemia virus type I p30 nuclear/nucleolar retention is mediated through interactions with RNA and a constituent of the 60 S ribosomal subunit.Identifying the biomarker potential of telomerase activity and shelterin complex molecule, telomeric repeat binding factor 2 (TERF2), in multiple myeloma.Acquired TERT promoter mutations stimulate TERT transcription in mantle cell lymphoma.The HTLV-1 basic leucine zipper factor (HBZ) attenuates repair of double-stranded DNA breaks via non-homologous end joining (NHEJ).
P2860
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P2860
Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Increased expression of telome ...... ts with adult T-cell leukemia.
@ast
Increased expression of telome ...... ts with adult T-cell leukemia.
@en
type
label
Increased expression of telome ...... ts with adult T-cell leukemia.
@ast
Increased expression of telome ...... ts with adult T-cell leukemia.
@en
prefLabel
Increased expression of telome ...... ts with adult T-cell leukemia.
@ast
Increased expression of telome ...... ts with adult T-cell leukemia.
@en
P2093
P2860
P356
P1476
Increased expression of telome ...... ts with adult T-cell leukemia.
@en
P2093
Abhik Datta
Christophe Nicot
Jean-Francois Pouliquen
Marcia Bellon
Megan Brown
P2860
P304
P356
10.1002/IJC.22026
P577
2006-11-01T00:00:00Z