DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion - Wikidata - awgldk - TriplyDB

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

http://www.wikidata.org/entity/Q33759285

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Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based Therapy Therapeutic targeting of replicative immortality Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions Redox control of senescence and age-related disease Systemic DNA damage responses in aging and diseases Circadian molecular clock in lung pathophysiology microRNA-34a promotes DNA damage and mitotic catastrophe.Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells.Age-associated defects in EphA2 signaling impair the migration of human cardiac progenitor cells.Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice.Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers Reprogramming ovarian and breast cancer cells into non-cancerous cells by low-dose metformin or SN-38 through FOXO3 activation Cellular senescence and protein degradation: breaking down cancer Four faces of cellular senescence.Cellular senescence: a link between cancer and age-related degenerative disease?Glucocorticoids suppress selected components of the senescence-associated secretory phenotype.Aging, cellular senescence, and cancer Senescent cells and their secretory phenotype as targets for cancer therapy.Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing.Tackling the tumor microenvironment: what challenge does it pose to anticancer therapies?Oxidative stress damage as a detrimental factor in preterm birth pathology A novel single-cell method provides direct evidence of persistent DNA damage in senescent cells and aged mammalian tissues Cellular senescence: putting the paradoxes in perspective.CHK2 kinase in the DNA damage response and beyond p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype.In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells.The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence.Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation.Multiple facets of histone variant H2AX: a DNA double-strand-break marker with several biological functions.Cellular senescence and the aging brain.Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype Persistent DNA damage-induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells.The role of nuclear lamin B1 in cell proliferation and senescence.NCI's provocative questions on cancer: some answers to ignite discussion.Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition?DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells.Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stability Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging.Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFβ1 signaling to confer a pro-survival bystander effect.

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P2860

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

http://www.wikidata.org/entity/Q33759285

description

2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年学术文章

@wuu

2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

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name

DNA-SCARS: distinct nuclear st ...... nflammatory cytokine secretion

@ast

DNA-SCARS: distinct nuclear st ...... nflammatory cytokine secretion

@en

type

label

DNA-SCARS: distinct nuclear st ...... nflammatory cytokine secretion

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DNA-SCARS: distinct nuclear st ...... nflammatory cytokine secretion

@en

prefLabel

DNA-SCARS: distinct nuclear st ...... nflammatory cytokine secretion

@ast

DNA-SCARS: distinct nuclear st ...... nflammatory cytokine secretion

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Journal of Cell Science

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DNA-SCARS: distinct nuclear st ...... nflammatory cytokine secretion

@en

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Albert R Davalos

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Christian M Beauséjour

http://www.w3.org/2001/XMLSchema#string

Denise P Muñoz

http://www.w3.org/2001/XMLSchema#string

Dipa Bhaumik

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Eric Campeau

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Francis Rodier

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Jean-Philippe Coppé

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Judith Campisi

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Oanh Le

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Robert Teachenor

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P2860

Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence

Oncogene-Induced Senescence: Putting the Brakes on Tumor Development

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

Feedback between p21 and reactive oxygen production is necessary for cell senescence

PML colocalizes with and stabilizes the DNA damage response protein TopBP1

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Megabase chromatin domains involved in DNA double-strand breaks in vivo

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68-81

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scholarly article

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10.1242/JCS.071340

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P407

P433

Pt 1

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P478

124

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2010-11-30T00:00:00Z

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49646405

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21118958

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3001408

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