Quality control of gene expression: a stepwise assembly pathway for the surveillance complex that triggers nonsense-mediated mRNA decay
about
Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and miceSMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoanUnusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2Essential role for fibrillin-2 in zebrafish notochord and vascular morphogenesisCompetency for nonsense-mediated reduction in collagen X mRNA is specified by the 3' UTR and corresponds to the position of mutations in Schmid metaphyseal chondrodysplasiaStructures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complexInsights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complexStructural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2Gene expression regulation by upstream open reading frames and human diseaseTelomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome endsInterplay between exonic splicing enhancers, mRNA processing, and mRNA surveillance in the dystrophic Mdx mouseMutations in SMG9, Encoding an Essential Component of Nonsense-Mediated Decay Machinery, Cause a Multiple Congenital Anomaly Syndrome in Humans and MiceComparison of nonsense-mediated mRNA decay efficiency in various murine tissues.Contribution of copy number variants involving nonsense-mediated mRNA decay pathway genes to neuro-developmental disorders.Transcripts expressed using a bicistronic vector pIREShyg2 are sensitized to nonsense-mediated mRNA decay.A molecular analysis of mutations at the complex dumpy locus in Drosophila melanogaster.The code within the code: microRNAs target coding regions.Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish.Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway.Translation of nonSTOP mRNA is repressed post-initiation in mammalian cellsPerispeckles are major assembly sites for the exon junction core complex.Caenorhabditis elegans SMG-2 selectively marks mRNAs containing premature translation termination codons.Approaches to lipid metabolism gene identification and characterization in the postgenomic era.mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons.A genome-wide RNAi screen identifies genes regulating the formation of P bodies in C. elegans and their functions in NMD and RNAi.Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region.Processing bodies are not required for mammalian nonsense-mediated mRNA decayTP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions.Mutations in PCBD1 cause hypomagnesemia and renal magnesium wasting.Assembly of mRNA-protein complexes for directional mRNA transport in eukaryotes--an overview.Nonsense suppression therapies in ocular genetic diseases.Genome-wide identification and analysis of small RNAs originated from natural antisense transcripts in Oryza sativaThe RNA Polymerase II C-Terminal Domain Phosphatase-Like Protein FIERY2/CPL1 Interacts with eIF4AIII and Is Essential for Nonsense-Mediated mRNA Decay in Arabidopsis.The 3' untranslated region of sindbis virus represses deadenylation of viral transcripts in mosquito and Mammalian cells.Interaction of PABPC1 with the translation initiation complex is critical to the NMD resistance of AUG-proximal nonsense mutations.Nonsense-mediated mRNA decay mutation in Aspergillus nidulans.Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival.Conventional 3' end formation is not required for NMD substrate recognition in Saccharomyces cerevisiae.On the right track: following the nucleo-cytoplasmic path of an mRNA.A cluster of disease resistance genes in Arabidopsis is coordinately regulated by transcriptional activation and RNA silencing.
P2860
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P2860
Quality control of gene expression: a stepwise assembly pathway for the surveillance complex that triggers nonsense-mediated mRNA decay
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Quality control of gene expres ...... s nonsense-mediated mRNA decay
@ast
Quality control of gene expres ...... s nonsense-mediated mRNA decay
@en
Quality control of gene expres ...... s nonsense-mediated mRNA decay
@nl
type
label
Quality control of gene expres ...... s nonsense-mediated mRNA decay
@ast
Quality control of gene expres ...... s nonsense-mediated mRNA decay
@en
Quality control of gene expres ...... s nonsense-mediated mRNA decay
@nl
prefLabel
Quality control of gene expres ...... s nonsense-mediated mRNA decay
@ast
Quality control of gene expres ...... s nonsense-mediated mRNA decay
@en
Quality control of gene expres ...... s nonsense-mediated mRNA decay
@nl
P356
P1433
P1476
Quality control of gene expres ...... s nonsense-mediated mRNA decay
@en
P356
10.1101/GAD.1407606
P407
P577
2006-02-15T00:00:00Z