PAK1 negatively regulates the activity of the Rho exchange factor NET1 - Wikidata - awgldk - TriplyDB

PAK1 negatively regulates the activity of the Rho exchange factor NET1

PAK1 negatively regulates the activity of the Rho exchange factor NET1

http://www.wikidata.org/entity/Q28305198

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The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity Phosphorylation-mediated regulation of GEFs for RhoA Rho GTPases in collective cell migration Acetylation of the RhoA GEF Net1A controls its subcellular localization and activity.PAK as a therapeutic target in gastric cancer Rac1 controls the subcellular localization of the Rho guanine nucleotide exchange factor Net1A to regulate focal adhesion formation and cell spreading Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth - SYDE1 regulates placental cell migration and invasion A bacterial cytotoxin identifies the RhoA exchange factor Net1 as a key effector in the response to DNA damage RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals Simultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promoters.RhoA phosphorylation induces Rac1 release from guanine dissociation inhibitor alpha and stimulation of vascular smooth muscle cell migration A transcriptional cross-talk between RhoA and c-Myc inhibits the RhoA/Rock-dependent cytoskeleton.PAK1 as a therapeutic target.Activin B antagonizes RhoA signaling to stimulate mesenchymal morphology and invasiveness of clear cell renal cell carcinomas.Dual roles for Rac2 in neutrophil motility and active retention in zebrafish hematopoietic tissue.Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk Rho kinase (ROCK) inhibitors.Timing is everything: Rac1 controls Net1A localization to regulate cell adhesion Protein kinase C epsilon: an oncogene and emerging tumor biomarker.The p21-activated kinase is required for neuronal migration in the cerebral cortex.Rho GTPase-independent regulation of mitotic progression by the RhoGEF Net1 Coexpression of alpha6beta4 integrin and guanine nucleotide exchange factor Net1 identifies node-positive breast cancer patients at high risk for distant metastasis.Pak protein kinases and their role in cancer.Interaction of the RhoA exchange factor Net1 with discs large homolog 1 protects it from proteasome-mediated degradation and potentiates Net1 activity Rho protein crosstalk: another social network?PAK signaling in cancer.PLAGL2 regulates actin cytoskeletal architecture and cell migration.Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms.A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion Filamin A links sphingosine kinase 1 and sphingosine-1-phosphate receptor 1 at lamellipodia to orchestrate cell migration.Disruption of RhoGDI and RhoA regulation by a Rac1 specificity switch mutant.Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function.The guanine nucleotide exchange factor Net1 facilitates the specification of dorsal cell fates in zebrafish embryos by promoting maternal β-catenin activation.

P2860

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P2860

PAK1 negatively regulates the activity of the Rho exchange factor NET1

http://www.wikidata.org/entity/Q28305198

description

2005 nî lūn-bûn

@nan

2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

PAK1 negatively regulates the activity of the Rho exchange factor NET1

@ast

PAK1 negatively regulates the activity of the Rho exchange factor NET1

@en

PAK1 negatively regulates the activity of the Rho exchange factor NET1

@nl

type

label

PAK1 negatively regulates the activity of the Rho exchange factor NET1

@ast

PAK1 negatively regulates the activity of the Rho exchange factor NET1

@en

PAK1 negatively regulates the activity of the Rho exchange factor NET1

@nl

prefLabel

PAK1 negatively regulates the activity of the Rho exchange factor NET1

@ast

PAK1 negatively regulates the activity of the Rho exchange factor NET1

@en

PAK1 negatively regulates the activity of the Rho exchange factor NET1

@nl

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P1433

Journal of Biological Chemistry

P1476

PAK1 negatively regulates the activity of the Rho exchange factor NET1

@en

P2093

Arthur S Alberts

http://www.w3.org/2001/XMLSchema#string

Heather S Carr

http://www.w3.org/2001/XMLSchema#string

Huajun Qin

http://www.w3.org/2001/XMLSchema#string

Jeffrey A Frost

http://www.w3.org/2001/XMLSchema#string

P2860

The Sequence of the Human Genome

PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells

Regulatory and signaling properties of the Vav family

Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling

Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis

Rho GTPases in cell biology

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

Regulation and functions of Rho-associated kinase

Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation

Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation

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12152-61

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scholarly article

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10.1074/JBC.M405073200

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13

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280

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2005-04-01T00:00:00Z

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8048786

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15684429

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