Rab27a regulates the peripheral distribution of melanosomes in melanocytes
about
Role of the small GTPase Rab27a during herpes simplex virus infection of oligodendrocytic cellsMyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomesA family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transportConstitutive GDP/GTP exchange and secretion-dependent GTP hydrolysis activity for Rab27 in plateletsRab27b is up-regulated in human Griscelli syndrome type II melanocytes and linked to the actin cytoskeleton via exon F-Myosin Va transcriptsMyosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cellsSlp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapseRab27a and Rab27b control different steps of the exosome secretion pathwayRab27a is an essential component of melanosome receptor for myosin VaThe Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphataseGranuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1aThe Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granulesThe Rab GTPase familyFunctional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndromeMutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden miceEvidence that Griscelli syndrome with neurological involvement is caused by mutations in RAB27A, not MYO5AHematopoietic- and neurologic-expressed sequence 1 (Hn1) depletion in B16.F10 melanoma cells promotes a differentiated phenotype that includes increased melanogenesis and cell cycle arrestAftiphilin and gamma-synergin are required for secretagogue sensitivity of Weibel-Palade bodies in endothelial cellsInsulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesinChromosomal mapping, gene structure and characterization of the human and murine RAB27B geneRapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse models.Rab and Arf proteins in genetic diseasesDirect imaging of RAB27B-enriched secretory vesicle biogenesis in lacrimal acinar cells reveals origins on a nascent vesicle budding siteRab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphateMelanosomal dynamics assessed with a live-cell fluorescent melanosomal markerRab GTPases, membrane trafficking and diseasesYpt32 recruits the Sec4p guanine nucleotide exchange factor, Sec2p, to secretory vesicles; evidence for a Rab cascade in yeast.Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiaeMlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p.Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeastSlac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transportSlp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cellsThe Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domainIdentification of EPI64 as a GTPase-activating protein specific for Rab27ARhoA regulates peroxisome association to microtubules and the actin cytoskeletonIdentification of an organelle receptor for myosin-VaThe leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytesRabphilin and Noc2 are recruited to dense-core vesicles through specific interaction with Rab27A in PC12 cellsEndo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosinMyosin Va mediates Rab8A-regulated GLUT4 vesicle exocytosis in insulin-stimulated muscle cells
P2860
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P2860
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
description
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Februar 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/02/19)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/02/19)
@nl
наукова стаття, опублікована в лютому 2001
@uk
مقالة علمية (نشرت في 19-2-2001)
@ar
name
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
@ast
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
@en
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
@nl
type
label
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
@ast
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
@en
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
@nl
prefLabel
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
@ast
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
@en
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
@nl
P2093
P2860
P921
P3181
P356
P1476
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
@en
P2093
A. N. Hume
A. Q. Gomes
C. R. Hopkins
L. M. Collinson
M. C. Seabra
P2860
P304
P3181
P356
10.1083/JCB.152.4.795
P407
P577
2001-02-19T00:00:00Z