Point mutation in the first transmembrane region of the beta 2 subunit of the gamma--aminobutyric acid type A receptor alters desensitization kinetics of gamma--aminobutyric acid- and anesthetic-induced channel gating
about
Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptorMapping convulsants' binding to the GABA-A receptor chloride ionophore: a proposed model for channel binding sites.The structural basis of function in Cys-loop receptors.GABA(A) receptors as molecular targets of general anesthetics: identification of binding sites provides clues to allosteric modulation.An outline of desensitization in pentameric ligand-gated ion channel receptors.The structural mechanism of the Cys-loop receptor desensitization.A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation.
P2860
Q35516107-33353367-CD35-4737-A248-31A09D0B64B8Q35924807-2E358DA9-62EE-4526-BCD1-DB30BD11F60EQ37789790-477FF045-4CD5-41A9-869A-568176B9E606Q37824834-65C64704-05CC-4CF1-8D15-F95E6E101CBCQ38039375-4F298686-B8C5-4C19-B633-AE229D6C1E7BQ38080450-BBC2EA44-3A4E-49F3-A3EC-EC4CCBC69B68Q42606895-40787872-AD8F-4F23-9075-B26811439479
P2860
Point mutation in the first transmembrane region of the beta 2 subunit of the gamma--aminobutyric acid type A receptor alters desensitization kinetics of gamma--aminobutyric acid- and anesthetic-induced channel gating
description
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
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im Mai 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/05/17)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/05/17)
@nl
наукова стаття, опублікована в травні 2002
@uk
name
Point mutation in the first tr ...... sthetic-induced channel gating
@ast
Point mutation in the first tr ...... sthetic-induced channel gating
@en
Point mutation in the first tr ...... sthetic-induced channel gating
@nl
type
label
Point mutation in the first tr ...... sthetic-induced channel gating
@ast
Point mutation in the first tr ...... sthetic-induced channel gating
@en
Point mutation in the first tr ...... sthetic-induced channel gating
@nl
prefLabel
Point mutation in the first tr ...... sthetic-induced channel gating
@ast
Point mutation in the first tr ...... sthetic-induced channel gating
@en
Point mutation in the first tr ...... sthetic-induced channel gating
@nl
P2093
P2860
P356
P1476
Point mutation in the first tr ...... sthetic-induced channel gating
@en
P2093
A. Christine Engblom
Arne Schousboe
Berit X. Carlson
Richard W. Olsen
Uffe Kristiansen
P2860
P304
17438–17447
P356
10.1074/JBC.M111215200
P407
P577
2002-05-17T00:00:00Z