Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
about
Notum deacylates Wnt proteins to suppress signalling activityThe clinical spectrum of homozygous HOXA1 mutationsZebrafish in the study of early cardiac developmentGenetics of congenital heart disease: the glass half emptyOf mice and men: molecular genetics of congenital heart diseaseConnecting teratogen-induced congenital heart defects to neural crest cells and their effect on cardiac functionThe neural crest in cardiac congenital anomaliesCiona as a Simple Chordate Model for Heart Development and RegenerationTBX1 Represses Vegfr2 Gene Expression and Enhances the Cardiac Fate of VEGFR2+ CellsAn Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation.Tbx1 regulates the BMP-Smad1 pathway in a transcription independent manner.Transcriptional control in cardiac progenitors: Tbx1 interacts with the BAF chromatin remodeling complex and regulates Wnt5aHes1 is expressed in the second heart field and is required for outflow tract developmentDefective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defectsTargeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract developmentThe del22q11.2 candidate gene Tbx1 regulates branchiomeric myogenesisPrdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryoTbx1 regulates population, proliferation and cell fate determination of otic epithelial cellsMorphogenesis of the right ventricle requires myocardial expression of Gata4Tbx1 regulates proliferation and differentiation of multipotent heart progenitorsRequired, tissue-specific roles for Fgf8 in outflow tract formation and remodelingHes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndromeFgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutantsBmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanismPitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardiumGreat vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in miceTbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndromeMesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract developmentTbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectodermA Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesisEarly thyroid development requires a Tbx1-Fgf8 pathwayIn vivo genetic ablation of the periotic mesoderm affects cell proliferation survival and differentiation in the cochlea.Tbx1 regulates Vegfr3 and is required for lymphatic vessel developmentMOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndromeT-box genes coordinate regional rates of proliferation and regional specification during cardiogenesisMesodermal Tbx1 is required for patterning the proximal mandible in miceTbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21Evolutionary and developmental origins of the cardiac neural crest: building a divided outflow tractBuilding the mammalian heart from two sources of myocardial cellsPitx2-mediated cardiac outflow tract remodeling.
P2860
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P2860
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
description
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Juli 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/07/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/07/01)
@nl
наукова стаття, опублікована в липні 2004
@uk
مقالة علمية (نشرت في يوليو 2004)
@ar
name
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
@ast
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
@en
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
@nl
type
label
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
@ast
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
@en
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
@nl
prefLabel
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
@ast
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
@en
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
@nl
P2093
P3181
P356
P1433
P1476
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
@en
P2093
Antonio Baldini
Benoit G. Bruneau
Elizabeth A. Lindsay
Huansheng Xu
John N. Wylie
Masae Morishima
Robert J. Schwartz
P304
P3181
P356
10.1242/DEV.01174
P407
P577
2004-07-01T00:00:00Z