ERK and the F-box protein betaTRCP target STAT1 for degradation - Wikidata - awgldk - TriplyDB

ERK and the F-box protein betaTRCP target STAT1 for degradation

ERK and the F-box protein betaTRCP target STAT1 for degradation

http://www.wikidata.org/entity/Q28590914

about

GSK-3 phosphorylates delta-catenin and negatively regulates its stability via ubiquitination/proteosome-mediated proteolysis Ubiquitination-mediated regulation of interferon responses The 19 s proteasome subcomplex establishes a specific protein interaction network at the promoter for stimulated transcriptional initiation in vivo.Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome Dietary apigenin potentiates the inhibitory effect of interferon-α on cancer cell viability through inhibition of 26S proteasome-mediated interferon receptor degradation Thiazolidinediones mimic glucose starvation in facilitating Sp1 degradation through the up-regulation of beta-transducin repeat-containing protein.How ubiquitination regulates the TGF-β signalling pathway: new insights and new players: new isoforms of ubiquitin-activating enzymes in the E1-E3 families join the game.The ubiquitin-proteasome system and signal transduction pathways regulating Epithelial Mesenchymal transition of cancer.ERK expression and its correlation with STAT1 in esophageal squamous cell carcinoma.A class IA PI3K controls inflammatory cytokine production in human neutrophils.beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt.Hsp27 and F-box protein β-TrCP promote degradation of mRNA decay factor AUF1.Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP.Role of STAT1 in the breast.Mimosa: mixture model of co-expression to detect modulators of regulatory interaction.Involvement of mitogen-activated protein kinase in signal transducer and activator of transcription-1 mediated differentiation induced by bortezomib in acute myeloid leukemia cells.E3 ubiquitin ligases in cancer and implications for therapies.ERK is a negative feedback regulator for IFN-γ/STAT1 signaling by promoting STAT1 ubiquitination.

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ERK and the F-box protein betaTRCP target STAT1 for degradation

http://www.wikidata.org/entity/Q28590914

description

2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հունիսին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 2008

@ast

im Juni 2008 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2008/06/06)

@sk

vědecký článek publikovaný v roce 2008

@cs

wetenschappelijk artikel (gepubliceerd op 2008/06/06)

@nl

наукова стаття, опублікована в червні 2008

@uk

name

ERK and the F-box protein betaTRCP target STAT1 for degradation

@ast

ERK and the F-box protein betaTRCP target STAT1 for degradation

@en

ERK and the F-box protein betaTRCP target STAT1 for degradation

@nl

type

label

ERK and the F-box protein betaTRCP target STAT1 for degradation

@ast

ERK and the F-box protein betaTRCP target STAT1 for degradation

@en

ERK and the F-box protein betaTRCP target STAT1 for degradation

@nl

prefLabel

ERK and the F-box protein betaTRCP target STAT1 for degradation

@ast

ERK and the F-box protein betaTRCP target STAT1 for degradation

@en

ERK and the F-box protein betaTRCP target STAT1 for degradation

@nl

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P356

P1433

Journal of Biological Chemistry

P1476

ERK and the F-box protein betaTRCP target STAT1 for degradation

@en

P2093

Anastasis Stephanou

http://www.w3.org/2001/XMLSchema#string

David S. Latchman

http://www.w3.org/2001/XMLSchema#string

Paul A. Townsend

http://www.w3.org/2001/XMLSchema#string

Richard A. Knight

http://www.w3.org/2001/XMLSchema#string

Sean P. Barry

http://www.w3.org/2001/XMLSchema#string

Surinder M. Soond

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation.

Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression.

Stats: transcriptional control and biological impact

P304

16077–16083

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scholarly article

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449623

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P356

10.1074/JBC.M800384200

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P433

23

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283

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2008-06-06T00:00:00Z

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P698

18378670

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P932

3259647

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