Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex - Wikidata - awgldk - TriplyDB

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

http://www.wikidata.org/entity/Q28609062

about

Whole-Genome Resequencing of Experimental Populations Reveals Polygenic Basis of Egg-Size Variation in Drosophila melanogaster Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling Structural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1)Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling Wnt/beta-catenin signaling and small molecule inhibitors Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomalies Wnt/beta-catenin signaling: components, mechanisms, and diseases SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability Wnt signaling: the good and the bad The links between axin and carcinogenesis Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling A transcriptional response to Wnt protein in human embryonic carcinoma cells Toggling a conformational switch in Wnt/β-catenin signaling: regulation of Axin phosphorylation. The phosphorylation state of Axin controls its scaffold function in two Wnt pathway protein complexes Ligand-independent traffic of Notch buffers activated Armadillo in Drosophila A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin E-cadherin-catenin cell-cell adhesion complex and human cancer IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin Curcumin-induced suppression of adipogenic differentiation is accompanied by activation of Wnt/beta-catenin signaling Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction.Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin Inhibition of Wnt signaling pathway by a novel axin-binding protein Axin2 regulates chondrocyte maturation and axial skeletal development Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin Murine Frizzled-1 behaves as an antagonist of the canonical Wnt/beta-catenin signaling Identification of zinc-finger BED domain-containing 3 (Zbed3) as a novel Axin-interacting protein that activates Wnt/beta-catenin signaling Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway.LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin Phosphoprotein phosphatase-2A docks to Dishevelled and counterregulates Wnt3a/beta-catenin signaling.The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2)Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells.The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin.

P2860

Q22066005-60616B2A-DBF7-46C2-8CF7-C0009EC698B0 Q24292002-CE210E42-90D3-4370-A94F-DB7C08793AD9 Q24292013-2A58180F-4CC5-401B-B54D-62876C7ED5B0 Q24295199-34A11DD2-D045-4E00-9C85-F9934C7E3639 Q24295277-9F0EDA2C-0DAF-4813-958E-22B990AD4C87 Q24298111-375F21F9-D6F0-4338-9030-CB4D8B05E446 Q24299327-E2618215-3E86-4A9C-A31E-22F5CCC2B84F Q24299895-95C833DD-71A6-4365-B152-CBB3B18C7350 Q24337495-AF37E76A-5561-441C-A146-A1C9B214DAA5 Q24597197-19D02594-CF21-4A77-9C6C-CAE3241034BF Q24626495-E7A8C28D-A502-4F83-91E0-DE9661715129 Q24630938-FF7C5D01-1809-4A86-B3B9-1835B851359B Q24647790-5E885583-0791-4E05-BF6B-430395FB4D86 Q24653563-912E503E-F4D9-434A-917A-11A2E0B45CCA Q24672469-B0E39351-4B2E-4F17-96D0-FDEF663D9D30 Q24680214-74C5BE5F-8F23-46C5-A1E2-654D5F5A776F Q24795999-4200ED93-CE2C-4EC9-8908-05FCB89A744A Q24798735-509BF796-E878-499C-B146-9C5F3E97E56D Q26829995-CF692089-A35C-4183-8286-3FDCAB826C98 Q27329673-152003C2-8880-4C4F-9E32-DF4847B49068 Q28115262-F65275A7-CFE6-4BDC-8A56-0A55A27DB93E Q28142886-49387D86-152F-45D1-BDEC-CC6B53479124 Q28209157-27D72AD6-1696-4192-A66D-591D93E1A2BB Q28278371-AC1413F1-2C47-46D7-8990-24BDC8F6854C Q28287909-501323F0-BB6E-4D0E-AE3E-88B93CB65646 Q28345088-641EA183-93CA-4C95-8B9D-B67070651779 Q28509243-78337E9E-C52A-4CE9-A3C9-450564AB7413 Q28509692-CEA148FF-C3CF-4A1A-AEFE-279E0D7A80F5 Q28565473-A269933C-1411-4DF9-B2FB-AE4536E119E5 Q28587074-AFC6B713-47BC-499F-A1C8-1D1A41CB624C Q28587207-637BA507-2B1D-4867-BCEA-AEE7156DDD10 Q28587260-00A46A5F-EBC3-4A20-9922-30CD0A6B2D2A Q28591968-3A5F4459-A302-4A62-85F8-4D813CC60A8B Q28595033-7B1515E9-8437-4AB5-AA53-EBD54732D017 Q28640887-4116BD36-6FF7-4798-8521-D29F6942C2C9 Q28757894-B6480ED9-B87D-4142-9097-60192EC263CC Q30443896-62A94270-CEA6-4650-A463-B604CF449B26 Q30989535-DBAB095E-D6D0-4BCD-B2F1-EDCA1C2A1A55 Q33183622-A369ECE4-B3A0-4F3D-8FEE-D6733B1B1E61 Q33607743-1E7D99BD-2B99-4D1A-A12D-902B086EDD5C

P2860

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

http://www.wikidata.org/entity/Q28609062

description

1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 1999

@ast

im Juli 1999 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1999/07/15)

@sk

vědecký článek publikovaný v roce 1999

@cs

wetenschappelijk artikel (gepubliceerd op 1999/07/15)

@nl

наукова стаття, опублікована в липні 1999

@uk

مقالة علمية (نشرت في 15-7-1999)

@ar

name

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

@ast

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

@en

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

@nl

type

label

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

@ast

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

@en

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

@nl

prefLabel

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

@ast

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

@en

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

@nl

P1433

Q28609062-F6617484-73A8-43A8-BE9F-4D570595B0AF

P1476

Q28609062-BF962C49-B0DC-4919-B038-BF38FC262B9C

P2093

Q28609062-0B96199C-EF14-441C-B9A8-73C2D77F6CC0

Q28609062-336B3E8F-5AE5-46F8-AFA2-F5211488A19E

Q28609062-D6215CA1-6FBD-41EC-B23E-ED723268280D

P2860

Q28609062-02BC711E-0004-458D-B333-B6A6BAFE1C08

Q28609062-09D6FC71-32E1-4733-8CF7-DBE684409463

Q28609062-22B127DC-A43D-40A7-93D8-9952A6009890

Q28609062-2AA10499-418A-4214-8617-E70EB2BDF57F

Q28609062-32A4A0F2-CE6C-4A2B-8721-1F36F3A45B70

Q28609062-5436DCEB-AFCF-45AE-8781-4E7F18AA639C

Q28609062-5D744E39-7BDD-4F7B-8E2B-F21F254AFB4C

Q28609062-628E5ACB-CEF4-4DC2-8147-8AE67B55FD88

Q28609062-6CB57751-B6CF-4DCD-943F-CFEEF96B3585

Q28609062-6D106225-1831-4552-9BEB-A650984ECB7E

P304

Q28609062-B9D8C918-5222-4C68-8BD3-AF1FD74B4E9A

P31

Q28609062-927674C1-DA48-4A0F-B3FB-C737A93E4A66

P3181

Q28609062-12EEA9B8-058A-44CB-ACA4-CCBDE6AC933F

P356

Q28609062-03DBFFF7-3235-4D56-9EF4-890DD09A1E50

P433

Q28609062-1990207A-3F50-48AA-BE64-61512CBE671B

P478

Q28609062-019007E8-5F46-4A06-A828-49209D73A27E

P577

Q28609062-96C1A3FA-94BD-481A-A6D0-E0871B0AFA85

P5875

Q28609062-BDBF9691-0149-41BB-9A10-A23744A148A5

P698

Q28609062-2AC58F46-284E-4A23-B779-7ED29393D8EE

P932

Q28609062-C221F144-CC2E-4B43-A115-0AB3EE7FC87E

P3181

P356

P1433

Genes & Development

P1476

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

@en

P2093

K. Willert

http://www.w3.org/2001/XMLSchema#string

R. Nusse

http://www.w3.org/2001/XMLSchema#string

S. Shibamoto

http://www.w3.org/2001/XMLSchema#string

P2860

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

A molecular mechanism for the effect of lithium on development

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level

Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

P304

1768–1773

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1903959

http://www.w3.org/2001/XMLSchema#string

P356

10.1101/GAD.13.14.1768

http://www.w3.org/2001/XMLSchema#string

P433

14

http://www.w3.org/2001/XMLSchema#string

P478

13

http://www.w3.org/2001/XMLSchema#string

P577

1999-07-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

12877216

http://www.w3.org/2001/XMLSchema#string

P698

10421629

http://www.w3.org/2001/XMLSchema#string

P932

316878

http://www.w3.org/2001/XMLSchema#string