Insights into the regulatory mechanism for caspase-8 activation
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Lifeguard/neuronal membrane protein 35 regulates Fas ligand-mediated apoptosis in neurons via microdomain recruitmentRipped to deathEngineering a dimeric caspase-9: a re-evaluation of the induced proximity model for caspase activationProtease signalling: the cutting edgeMembrane trafficking of death receptors: implications on signallingIn vivo imaging of hierarchical spatiotemporal activation of caspase-8 during apoptosisCrystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathwayFas-Fas Ligand: Checkpoint of T Cell Functions in Multiple SclerosisFLIP and the death effector domain familyN-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathwayMolecular mechanisms of caspase regulation during apoptosisCharacterization of cytoplasmic caspase-2 activation by induced proximity.Activation mechanism and substrate specificity of the Drosophila initiator caspase DRONC.Constitutive expression of murine c-FLIPR causes autoimmunity in aged miceInduction of apoptosis by Shiga toxins.Quantitative analysis of pathways controlling extrinsic apoptosis in single cellsSupplementation with conjugated linoeic acid decreases pig back fat deposition by inducing adipocyte apoptosis.Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation.Bortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathwaysSelective inactivation of a Fas-associated death domain protein (FADD)-dependent apoptosis and autophagy pathway in immortal epithelial cells.Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppressionCaspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine.Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibitionA death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death.Direct binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD.Activation of caspases-8 and -10 by FLIP(L).Necroptotic signaling in adaptive and innate immunity.Intra- and interdimeric caspase-8 self-cleavage controls strength and timing of CD95-induced apoptosis.Unique and overlapping substrate specificities of caspase-8 and caspase-10.The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer.Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3.Effects and mechanisms of alveolar type II epithelial cell apoptosis in severe pancreatitis-induced acute lung injury.Chemotherapeutic approaches for targeting cell death pathways.The role of c-FLIP splice variants in urothelial tumours.Heterogeneity of primary glioblastoma cells in the expression of caspase-8 and the response to TRAIL-induced apoptosis.FADD cleavage by NK cell granzyme M enhances its self-association to facilitate procaspase-8 recruitment for auto-processing leading to caspase cascadeCaspase activation, inhibition, and reactivation: a mechanistic view.The protein structures that shape caspase activity, specificity, activation and inhibition.A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma.Tyrosine Phosphorylation of Caspase-8 Abrogates Its Apoptotic Activity and Promotes Activation of c-Src
P2860
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P2860
Insights into the regulatory mechanism for caspase-8 activation
description
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Februar 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/02/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/02/01)
@nl
наукова стаття, опублікована в лютому 2003
@uk
مقالة علمية (نشرت في فبراير 2003)
@ar
name
Insights into the regulatory mechanism for caspase-8 activation
@ast
Insights into the regulatory mechanism for caspase-8 activation
@en
Insights into the regulatory mechanism for caspase-8 activation
@nl
type
label
Insights into the regulatory mechanism for caspase-8 activation
@ast
Insights into the regulatory mechanism for caspase-8 activation
@en
Insights into the regulatory mechanism for caspase-8 activation
@nl
prefLabel
Insights into the regulatory mechanism for caspase-8 activation
@ast
Insights into the regulatory mechanism for caspase-8 activation
@en
Insights into the regulatory mechanism for caspase-8 activation
@nl
P2093
P3181
P1433
P1476
Insights into the regulatory mechanism for caspase-8 activation
@en
P2093
Christophe Briand
Markus G. Grütter
Mrudula Donepudi
P304
P3181
P356
10.1016/S1097-2765(03)00059-5
P577
2003-02-01T00:00:00Z