C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
about
A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stabilityRTEL1 maintains genomic stability by suppressing homologous recombinationTti1 and Tel2 are critical factors in mammalian target of rapamycin complex assemblyUncoupling of longevity and telomere length in C. elegans.High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegansA link between meiotic prophase progression and crossover controlCaenorhabditis elegans protein arginine methyltransferase PRMT-5 negatively regulates DNA damage-induced apoptosisFunctional dissection of Caenorhabditis elegans CLK-2/TEL2 cell cycle defects during embryogenesis and germline developmentLEM-3 - A LEM domain containing nuclease involved in the DNA damage response in C. elegansThe Caenorhabditis elegans THO complex is required for the mitotic cell cycle and developmentRelationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegansTel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break.Human CLK2 links cell cycle progression, apoptosis, and telomere length regulationCell-nonautonomous regulation of C. elegans germ cell death by kri-1HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stabilityThe Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repairThe BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping servicesA systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevityRAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair.Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans.Transcriptional profiling in C. elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family.The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegansThe Caenorhabditis elegans Werner syndrome protein functions upstream of ATR and ATM in response to DNA replication inhibition and double-strand DNA breaks.Genetic and physical interactions between Tel2 and the Med15 Mediator subunit in Saccharomyces cerevisiae.Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line.Long lifespan in worms with long telomeric DNA.Molecular control of TiO₂-NPs toxicity formation at predicted environmental relevant concentrations by Mn-SODs proteins.Drosophila Tel2 is expressed as a translational fusion with EpsinR and is a regulator of wingless signalingA Caenorhabditis elegans tissue model of radiation-induced reproductive cell death.Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegansHomologous recombination is required for genome stability in the absence of DOG-1 in Caenorhabditis elegansDevelopmental modulation of nonhomologous end joining in Caenorhabditis elegans.C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway required for germ cell survival.Mutator phenotype of Caenorhabditis elegans DNA damage checkpoint mutantsThe EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegansQuantitative proteomic identification of the BRCA1 ubiquitination substrates.The Caenorhabditis elegans Rad17 homolog HPR-17 is required for telomere replication.XRad17 is required for the activation of XChk1 but not XCds1 during checkpoint signaling in Xenopus.Differential regulation of DNA damage response activation between somatic and germline cells in Caenorhabditis elegans.Noncanonical control of C. elegans germline apoptosis by the insulin/IGF-1 and Ras/MAPK signaling pathways
P2860
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P2860
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
description
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Dezember 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/12/11)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/12/11)
@nl
наукова стаття, опублікована в грудні 2001
@uk
مقالة علمية (نشرت في 11-12-2001)
@ar
name
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
@ast
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
@en
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
@nl
type
label
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
@ast
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
@en
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
@nl
prefLabel
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
@ast
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
@en
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
@nl
P50
P3181
P1433
P1476
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein
@en
P2093
P304
P3181
P356
10.1016/S0960-9822(01)00604-2
P407
P577
2001-12-01T00:00:00Z