Var2CSA minimal CSA binding region is located within the N-terminal region
about
Antigen reversal identifies targets of opsonizing IgGs against pregnancy-associated malariaSurface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates.Sequence polymorphism, segmental recombination and toggling amino acid residues within the DBL3X domain of the VAR2CSA placental malaria antigen.Designing a VAR2CSA-based vaccine to prevent placental malaria.Cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced.VAR2CSA signatures of high Plasmodium falciparum parasitemia in the placentaThe antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding siteProtective Antibodies against Placental Malaria and Poor Outcomes during Pregnancy, BeninParity-dependent recognition of DBL1X-3X suggests an important role of the VAR2CSA high-affinity CSA-binding region in the development of the humoral response against placental malaria.Differential recognition of terminal extracellular Plasmodium falciparum VAR2CSA domains by sera from multigravid, malaria-exposed Malian women.Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria.Structure of the DBL3X-DBL4ε region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactionsIdentification of VAR2CSA domain-specific inhibitory antibodies of the Plasmodium falciparum erythrocyte membrane protein 1 using a novel flow cytometry assayClinical development of placental malaria vaccines and immunoassays harmonization: a workshop report.Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytes.Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers.Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.Characterization of human placental glycosaminoglycans and regional binding to VAR2CSA in malaria infected erythrocytes.Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domainPre-clinical and clinical development of the first placental malaria vaccine.The case for PfEMP1-based vaccines to protect pregnant women against Plasmodium falciparum malaria.A new method for sequencing the hypervariable Plasmodium falciparum gene var2csa from clinical samples.Use of the SHuffle Strains in Production of Proteins.Antibody levels to recombinant VAR2CSA domains vary with Plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes.IgG Responses to the Plasmodium falciparum Antigen VAR2CSA in Colombia Are Restricted to Pregnancy and Are Not Induced by Exposure to Plasmodium vivaxDown-selection of the VAR2CSA DBL1-2 expressed in as a lead antigen for placental malaria vaccine development
P2860
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P2860
Var2CSA minimal CSA binding region is located within the N-terminal region
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Var2CSA minimal CSA binding region is located within the N-terminal region
@ast
Var2CSA minimal CSA binding region is located within the N-terminal region
@en
Var2CSA minimal CSA binding region is located within the N-terminal region
@nl
type
label
Var2CSA minimal CSA binding region is located within the N-terminal region
@ast
Var2CSA minimal CSA binding region is located within the N-terminal region
@en
Var2CSA minimal CSA binding region is located within the N-terminal region
@nl
prefLabel
Var2CSA minimal CSA binding region is located within the N-terminal region
@ast
Var2CSA minimal CSA binding region is located within the N-terminal region
@en
Var2CSA minimal CSA binding region is located within the N-terminal region
@nl
P2093
P2860
P50
P3181
P1433
P1476
Var2CSA minimal CSA binding region is located within the N-terminal region
@en
P2093
Anita Lewit Bentley
Farroudja Amirat
Graham A Bentley
Stéphane Gangnard
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0020270
P407
P577
2011-05-19T00:00:00Z