Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria.
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The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria VaccinePlacental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1The role of PfEMP1 as targets of naturally acquired immunity to childhood malaria: prospects for a vaccineModeling cytoadhesion of Plasmodium falciparum-infected erythrocytes and leukocytes-common principles and distinctive featuresMalaria vaccine clinical trials: what's on the horizonReal-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting.Antigen reversal identifies targets of opsonizing IgGs against pregnancy-associated malariaFunctional antibodies against VAR2CSA in nonpregnant populations from colombia exposed to Plasmodium falciparum and Plasmodium vivax.Kinetics of B cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasitesHost-Parasite Interactions in Human Malaria: Clinical Implications of Basic ResearchDynamics in the cytoadherence phenotypes of Plasmodium falciparum infected erythrocytes isolated during pregnancy.Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSADesigning a VAR2CSA-based vaccine to prevent placental malaria.Factor H binds to the hypervariable region of many Streptococcus pyogenes M proteins but does not promote phagocytosis resistance or acute virulence.Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.Cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced.VAR2CSA signatures of high Plasmodium falciparum parasitemia in the placentaThe antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding siteUsing the PfEMP1 head structure binding motif to deal a blow at severe malaria.Protective Antibodies against Placental Malaria and Poor Outcomes during Pregnancy, BeninParity-dependent recognition of DBL1X-3X suggests an important role of the VAR2CSA high-affinity CSA-binding region in the development of the humoral response against placental malaria.Differential recognition of terminal extracellular Plasmodium falciparum VAR2CSA domains by sera from multigravid, malaria-exposed Malian women.Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA.IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria.A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA.Molecular dissection of placental malaria protein VAR2CSA interaction with a chemo-enzymatically synthesized chondroitin sulfate library.Structure of the DBL3X-DBL4ε region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactionsComparison of the specificity of antibodies to VAR2CSA in Cameroonian multigravidae with and without placental malaria: a retrospective case-control study.Complement Activation in Placental Malaria.Influence of Intermittent Preventive Treatment on Antibodies to VAR2CSA in Pregnant Cameroonian WomenIdentification of VAR2CSA domain-specific inhibitory antibodies of the Plasmodium falciparum erythrocyte membrane protein 1 using a novel flow cytometry assayTargeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein.Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria.Murine Model for Preclinical Studies of Var2CSA-Mediated Pathology Associated with Malaria in PregnancyGlycosaminoglycans and infection.Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report.Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytes.Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers.Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility.Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.
P2860
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P2860
Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Structural and functional insi ...... ulfate A in placental malaria.
@ast
Structural and functional insi ...... ulfate A in placental malaria.
@en
type
label
Structural and functional insi ...... ulfate A in placental malaria.
@ast
Structural and functional insi ...... ulfate A in placental malaria.
@en
prefLabel
Structural and functional insi ...... ulfate A in placental malaria.
@ast
Structural and functional insi ...... ulfate A in placental malaria.
@en
P2093
P2860
P50
P921
P356
P1476
Structural and functional insi ...... sulfate A in placental malaria
@en
P2093
Besim Berisha
Daniel Andersen
Kamilla E Jensen
Madeleine Dahlbäck
Mafalda Resende
Sisse B Ditlev
Stig Christoffersen
Thomas M Clausen
Vera V Pinto
P2860
P304
23332-23345
P356
10.1074/JBC.M112.348839
P407
P50
P577
2012-05-08T00:00:00Z