Strain-transcendent immune response to recombinant Var2CSA DBL5-ε domain block P. falciparum adhesion to placenta-derived BeWo cells under flow conditions.
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Differential induction of functional IgG using the Plasmodium falciparum placental malaria vaccine candidate VAR2CSAAn image-based drug susceptibility assay targeting the placental sequestration of Plasmodium falciparum-infected erythrocytesVar2CSA minimal CSA binding region is located within the N-terminal regionAntigen reversal identifies targets of opsonizing IgGs against pregnancy-associated malariaDesigning a VAR2CSA-based vaccine to prevent placental malaria.Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins.Cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced.High-throughput screening platform identifies small molecules that prevent sequestration of Plasmodium falciparum-infected erythrocytes.Prospects and Pitfalls of Pregnancy-Associated Malaria Vaccination Based on the Natural Immune Response to Plasmodium falciparum VAR2CSA-Expressing Parasites.Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria.Identification of VAR2CSA domain-specific inhibitory antibodies of the Plasmodium falciparum erythrocyte membrane protein 1 using a novel flow cytometry assayAntibodies to Escherichia coli-expressed C-terminal domains of Plasmodium falciparum variant surface antigen 2-chondroitin sulfate A (VAR2CSA) inhibit binding of CSA-adherent parasites to placental tissue.Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria.Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.Pre-clinical and clinical development of the first placental malaria vaccine.The case for PfEMP1-based vaccines to protect pregnant women against Plasmodium falciparum malaria.A new method for sequencing the hypervariable Plasmodium falciparum gene var2csa from clinical samples.VAR2CSA Domain-Specific Analysis of Naturally Acquired Functional Antibodies to Plasmodium falciparum Placental Malaria.Evaluation of Pregnancy Malaria Vaccine Candidates: The Binding Inhibition Assay.Functional analysis of Plasmodium vivax VIR proteins reveals different subcellular localizations and cytoadherence to the ICAM-1 endothelial receptor.Evaluating antibody functional activity and strain-specificity of vaccine candidates for malaria in pregnancy using in vitro phagocytosis assays.In vivo antitumor activity evaluation of cancer vaccines prepared by various antigen forms in a murine hepatocellular carcinoma model.
P2860
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P2860
Strain-transcendent immune response to recombinant Var2CSA DBL5-ε domain block P. falciparum adhesion to placenta-derived BeWo cells under flow conditions.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Strain-transcendent immune res ...... o cells under flow conditions.
@ast
Strain-transcendent immune res ...... o cells under flow conditions.
@en
type
label
Strain-transcendent immune res ...... o cells under flow conditions.
@ast
Strain-transcendent immune res ...... o cells under flow conditions.
@en
prefLabel
Strain-transcendent immune res ...... o cells under flow conditions.
@ast
Strain-transcendent immune res ...... o cells under flow conditions.
@en
P2093
P2860
P1433
P1476
Strain-transcendent immune res ...... o cells under flow conditions.
@en
P2093
Artur Scherf
Jürg Gysin
Pablo Fernandez
Salaheddine Mécheri
P2860
P304
P356
10.1371/JOURNAL.PONE.0012558
P407
P577
2010-09-03T00:00:00Z