Cell motility mediated by rho and rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma - Wikidata - awgldk - TriplyDB

Cell motility mediated by rho and rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma

Cell motility mediated by rho and rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma

http://www.wikidata.org/entity/Q29011830

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Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities Regulation of ROCK activity in cancer Higher LPA2 and LPA6 mRNA Levels in Hepatocellular Carcinoma Are Associated with Poorer Differentiation, Microvascular Invasion and Earlier Recurrence with Higher Serum Autotaxin Levels Bif-1 promotes tumor cell migration and metastasis via Cdc42 expression and activity.Molecular cloning and characterization of a novel gene which is highly expressed in hepatocellular carcinoma.The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways.Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance.Circulating DNA level is negatively associated with the long-term survival of hepatocellular carcinoma patients.Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma.Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.Metastatic human hepatocellular carcinoma models in nude mice and cell line with metastatic potential.Galectin 3 regulates HCC cell invasion by RhoA and MLCK activation.TGF beta1 and related-Smads contribute to pulmonary metastasis of hepatocellular carcinoma in mice model.Organ microenvironment affects growth and metastasis of hepatocellular carcinoma via the TGF-β/Smad pathway in mice.Gene expression profiles at different stages of human esophageal squamous cell carcinoma.Molecular pathways triggering glioma cell invasion.Co-culture of hepatoma cells with hepatocytic precursor (stem-like) cells inhibits tumor cell growth and invasion by downregulating Akt/NF-κB expression.Amplification of MPZL1/PZR promotes tumor cell migration through Src-mediated phosphorylation of cortactin in hepatocellular carcinoma.SERPINA5 inhibits tumor cell migration by modulating the fibronectin-integrin β1 signaling pathway in hepatocellular carcinoma.RhoE is frequently down-regulated in hepatocellular carcinoma (HCC) and suppresses HCC invasion through antagonizing the Rho/Rho-kinase/myosin phosphatase target pathway.The Rho kinase inhibitor fasudil is involved in p53-mediated apoptosis in human hepatocellular carcinoma cells.RNA interference targeting CITRON can significantly inhibit the proliferation of hepatocellular carcinoma cells.Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion.Rho-associated kinase inhibitor reduces tumor recurrence after liver transplantation in a rat hepatoma model.MEK/ERK signaling is a critical mediator for integrin-induced cell scattering in highly metastatic hepatocellular carcinoma cells.Integrin engagement differentially modulates epithelial cell motility by RhoA/ROCK and PAK1.Expression of somatostatin receptors in normal and cirrhotic human liver and in hepatocellular carcinoma.Enhancement of osteopontin expression in HepG2 cells by epidermal growth factor via phosphatidylinositol 3-kinase signaling pathway Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor.Expression of functional chemokine receptors CXCR3 and CXCR4 on human melanoma cells.Brachytherapy with Iodine-125 seeds strand for treatment of main portal vein tumor thrombi: an experimental study in a rabbit model Loss of cell-cell contact is induced by integrin-mediated cell-substratum adhesion in highly-motile and highly-metastatic hepatocellular carcinoma cells.Myosin phosphatase and RhoA-activated kinase modulate arginine methylation by the regulation of protein arginine methyltransferase 5 in hepatocellular carcinoma cells.Nude mice model of human hepatocellular carcinoma via orthotopic implantation of histologically intact tissue Afzelin exhibits anti-cancer activity against androgen-sensitive LNCaP and androgen-independent PC-3 prostate cancer cells through the inhibition of LIM domain kinase 1.Involvement of c-Src in carcinoma cell motility and metastasis.

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P2860

Cell motility mediated by rho and rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma

http://www.wikidata.org/entity/Q29011830

description

1999 nî lūn-bûn

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1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հոտեմբերին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Cell motility mediated by rho ...... human hepatocellular carcinoma

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Cell motility mediated by rho ...... human hepatocellular carcinoma

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type

label

Cell motility mediated by rho ...... human hepatocellular carcinoma

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Cell motility mediated by rho ...... human hepatocellular carcinoma

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prefLabel

Cell motility mediated by rho ...... human hepatocellular carcinoma

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Cell motility mediated by rho ...... human hepatocellular carcinoma

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Cell motility mediated by rho ...... human hepatocellular carcinoma

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Hitoshi Asakura

http://www.w3.org/2001/XMLSchema#string

Masamichi Kojiro

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Michiie Sakamoto

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Setsuo Hirohashi

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Shuh Narumiya

http://www.w3.org/2001/XMLSchema#string

Takafumi Ichida

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Takuya Genda

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1027-1036

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scholarly article

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3761815

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10.1002/HEP.510300420

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4

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30

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1999-10-01T00:00:00Z

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227828934

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10498656

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