about
Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsEssential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytesEpigenetic Codes Programing Class Switch Recombination53BP1: pro choice in DNA repairRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationIgH chain class switch recombination: mechanism and regulationAcetylation limits 53BP1 association with damaged chromatin to promote homologous recombination53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.A dual role for A-type lamins in DNA double-strand break repairGenomic instability in laminopathy-based premature agingDistinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesisA chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouseThe histone methyltransferase MMSET regulates class switch recombinationA PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complexThe RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombinationDouble strand break repair functions of histone H2AX53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaksRIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.TIRR regulates 53BP1 by masking its histone methyl-lysine binding functionRole of 53BP1 oligomerization in regulating double-strand break repair.BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination.Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism.PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.Generation and repair of AID-initiated DNA lesions in B lymphocytes.CtIP-mediated resection is essential for viability and can operate independently of BRCA1.ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination.Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells.DNA damage and laminsArtemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and developmentGenomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
name
53BP1 is required for class switch recombination.
@ast
53BP1 is required for class switch recombination.
@en
type
label
53BP1 is required for class switch recombination.
@ast
53BP1 is required for class switch recombination.
@en
prefLabel
53BP1 is required for class switch recombination.
@ast
53BP1 is required for class switch recombination.
@en
P2093
P2860
P3181
P356
P1476
53BP1 is required for class switch recombination.
@en
P2093
Alexandru Olaru
Andre Nussenzweig
Bernardo Reina-San-Martin
Ferenc Livak
Irene M Ward
Julie S Lau
Junjie Chen
Koji Tamada
Lieping Chen
P2860
P304
P3181
P356
10.1083/JCB.200403021
P407
P577
2004-05-01T00:00:00Z