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Phosphorylation of myosin light chain kinase by p21-activated kinase PAK2The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikisp21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factorAsef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation elementPaxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathwayPAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cellsS338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3Angiopoietin-like 4 interacts with matrix proteins to modulate wound healingThe plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand bindingThe nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization, and migrationCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activityStimulation of M3 muscarinic receptors induces phosphorylation of the Cdc42 effector activated Cdc42Hs-associated kinase-1 via a Fyn tyrosine kinase signaling pathwayMEK kinase 2 binds and activates protein kinase C-related kinase 2. Bifurcation of kinase regulatory pathways at the level of an MAPK kinase kinaseCell-type-specific activation of PAK2 by transforming growth factor beta independent of Smad2 and Smad3Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoAPAK4 kinase is essential for embryonic viability and for proper neuronal developmentAndrogen receptor specifically interacts with a novel p21-activated kinase, PAK6Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1Regulation of SPIN90 phosphorylation and interaction with Nck by ERK and cell adhesionActivated PAK4 regulates cell adhesion and anchorage-independent growthJAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functionsActivation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cellsp21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cellsFunctional deficits in PAK5, PAK6 and PAK5/PAK6 knockout miceP21-activated protein kinase (PAK2)-mediated c-Jun phosphorylation at 5 threonine sites promotes cell transformationIdentification and characterization of PS-GAP as a novel regulator of caspase-activated PAK-2Lentivirus Nef specifically activates Pak2.Vinexin beta regulates the anchorage dependence of ERK2 activation stimulated by epidermal growth factor.Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.PAK1-Nck regulates cyclin D1 promoter activity in response to prolactinThe LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL).The pak4 protein kinase plays a key role in cell survival and tumorigenesis in athymic miceHuman immunodeficiency virus type 1 Nef selectively associates with a catalytically active subpopulation of p21-activated kinase 2 (PAK2) independently of PAK2 binding to Nck or beta-PIXDifferential sensitivity of Pak5, Pak6, and Pak5/Pak6 double-knockout mice to the stimulant effects of amphetamine and exercise-induced alterations in body weight.Inhibition of p21 activated kinase (PAK) reduces airway responsiveness in vivo and in vitro in murine and human airways.Activation of Syk protein tyrosine kinase in response to osmotic stress requires interaction with p21-activated protein kinase Pak2/gamma-PAK.PAK1 and aPKCzeta regulate myosin II-B phosphorylation: a novel signaling pathway regulating filament assemblyRegulation of macropinocytosis by p21-activated kinase-1Myosin I heavy chain kinase: cloning of the full-length gene and acidic lipid-dependent activation by Rac and Cdc42.
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The p21Rac/Cdc42-activated kinases (PAKs).
@ast
The p21Rac/Cdc42-activated kinases (PAKs).
@en
type
label
The p21Rac/Cdc42-activated kinases (PAKs).
@ast
The p21Rac/Cdc42-activated kinases (PAKs).
@en
prefLabel
The p21Rac/Cdc42-activated kinases (PAKs).
@ast
The p21Rac/Cdc42-activated kinases (PAKs).
@en
P1476
The p21Rac/Cdc42-activated kinases (PAKs).
@en
P2093
P304
P356
10.1016/S1357-2725(98)00059-4
P577
1998-08-01T00:00:00Z