Trapping the on-pathway folding intermediate of Im7 at equilibrium.
about
Amino Acid Insertion Reveals a Necessary Three-Helical Intermediate in the Folding Pathway of the Colicin E7 Immunity Protein Im7The Plastic Energy Landscape of Protein Folding: A TRIANGULAR FOLDING MECHANISM WITH AN EQUILIBRIUM INTERMEDIATE FOR A SMALL PROTEIN DOMAINGenetic selection designed to stabilize proteins uncovers a chaperone called SpyUsing hydroxyl radical footprinting to explore the free energy landscape of protein folding.Desolvation and development of specific hydrophobic core packing during Im7 folding.Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation.Combining experiment and simulation in protein folding: closing the gap for small model systems.Determination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7.Probing a moving target with a plastic unfolding intermediate of an ankyrin-repeat protein.Protein hydrophobic collapse and early folding steps observed in a microfluidic mixer.Consequences of localized frustration for the folding mechanism of the IM7 protein.Substrate protein folds while it is bound to the ATP-independent chaperone SpyFolding versus aggregation: polypeptide conformations on competing pathwaysNuclease colicins and their immunity proteins.Understanding how small helical proteins fold: conformational dynamics of Im proteins relevant to their folding landscapes.Single-molecule studies of the Im7 folding landscape.The folding trajectory of RNase H is dominated by its topology and not local stability: a protein engineering study of variants that fold via two-state and three-state mechanisms.A single mutation at residue 25 populates the folding intermediate of E. coli RNase H and reveals a highly dynamic partially folded ensemble.NMR analysis of the conformational properties of the trapped on-pathway folding intermediate of the bacterial immunity protein Im7.Semisynthesis of a glycosylated Im7 analogue for protein folding studies.Dissecting key residues in folding and stability of the bacterial immunity protein 7Misfolding of a bacterial autotransporter.Mutational analysis of the stability of the H2A and H2B histone monomers.Conformational properties of the unfolded state of Im7 in nondenaturing conditionsInterrupted hydrogen/deuterium exchange reveals the stable core of the remarkably helical molten globule of alpha-beta parallel protein flavodoxin.Chaperone-substrate interactions monitored via a robust TEM-1 β-lactamase fragment complementation assay.
P2860
Q27656859-7066D006-D0DE-42C2-B665-7AD5DFEC425EQ27660382-AD64FEC5-CC45-4D7F-B781-8DA5B3DA3002Q27666964-BB9CFE2D-4321-420C-9F49-DC5CE9112035Q30372486-A127A89A-BA4B-499E-BEC4-EB36C7FF4714Q30384130-40CAA54B-D664-4AEF-B4DC-8FF153112A5FQ30397247-0E956CA4-6A5B-4282-A4E7-CA7CACB7C8BFQ31145148-A7DFA8DB-B8AD-4B81-A379-D712254C7D93Q34248287-7EC68DCB-45A6-439B-BFD3-EAB7CFA165F0Q35808762-E1636301-5916-4798-8769-7B4106522A2CQ35881232-C4CBE0C9-AD2A-4E3D-BCEE-E2DA9D87AFD6Q36288464-D4F9FBEB-39EB-42F2-A19E-5E792B48EF2FQ36843657-2F4174EC-5690-4143-BC60-57A45BD1B15DQ36858313-0D001016-1983-401C-A244-6082082CAE12Q37956420-72709505-6DF7-4823-B6E3-B1FAD86326AFQ37995732-3EC0C1E6-8AA9-4118-874F-20D2B291BD2BQ40043438-9DC9F9FA-E9ED-44D1-903A-BBC7192CC54FQ40388075-BA58A930-2E5D-40A9-8981-E9BA51DFD285Q40913581-00B5C665-E704-44D5-AD61-26EB7938C16AQ41837313-BAC58062-193F-4774-907B-6752FEA8592FQ41909977-2DB3A7DE-28E8-40C9-9182-2D7E7F598C2EQ42121441-4B7B68B1-8384-49F3-B80C-006BC1483A83Q42198344-B2B28E29-6C17-4306-A765-6B04FDEDBDF2Q42227728-B14F5F32-3BC3-4224-AF20-950F437DC985Q42563081-AEE61950-7E53-4D00-83C3-AF8B051B5683Q42912766-D94DB8B5-AF83-42E3-98F0-15461A34E57DQ48160549-3AAC59B7-D309-4099-843D-4B8CA6D29D88
P2860
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
@ast
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
@en
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
@en-gb
type
label
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
@ast
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
@en
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
@en-gb
prefLabel
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
@ast
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
@en
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
@en-gb
P1476
Trapping the on-pathway folding intermediate of Im7 at equilibrium.
@en
P2093
Andrew P Capaldi
Graham R Spence
P304
P356
10.1016/J.JMB.2004.05.049
P407
P577
2004-07-01T00:00:00Z