Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis.
about
Molecular genetics of neurofibromatosis type 1 (NF1)Molecular profiling of malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1, based on large-scale real-time RT-PCRA RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressorAntioncogenes and human cancer.Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytesGenetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivoNf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferaseMouse tumor model for neurofibromatosis type 1Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasmsGenetic predispositions and childhood cancer.Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal modelsNeurofibromatosis type 1 in children.Clinical and genetic patterns of neurofibromatosis 1 and 2.Adult soft tissue sarcoma.tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors.Pathology of tumors of the peripheral nerve sheath in type 1 neurofibromatosis.Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumoursNeurofibromin-deficient fibroblasts fail to form perineurium in vitro.Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis.CD44 and p53 immunoexpression patterns in NF1 neoplasms - indicators of malignancy and infiltration.Zebrafish models of p53 functions.Paternally derived translocation t(8;18)(q22.1;q22)pat associated in a patient with developmental delay: Case report and reviewTranscriptional profiling in an MPNST-derived cell line and normal human Schwann cellsNeurofibromatosis type 1-associated unusual pleomorphic astrocytoma displaying continual malignant progression.An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model.Protein expression of BIRC5, TK1, and TOP2A in malignant peripheral nerve sheath tumours--A prognostic test after surgical resection.Hepatitis B virus infection and primary hepatocellular carcinoma.Confirmation of a double-hit model for the NF1 gene in benign neurofibromas.Malignant peripheral nerve sheath tumour arising within neurofibroma. An immunohistochemical analysis in the comparison between benign and malignant components.Recurrent chromosomal imbalances and structurally abnormal breakpoints within complex karyotypes of malignant peripheral nerve sheath tumour and malignant triton tumour: a cytogenetic and molecular cytogenetic study.Genetics of neurofibromatosis 1-associated peripheral nerve sheath tumors.Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions.Expression of p27(kip) and other cell cycle regulators in malignant peripheral nerve sheath tumors and neurofibromas: the emerging role of p27(kip) in malignant transformation of neurofibromas.Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromasMalignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivationMMP-13 and p53 in the progression of malignant peripheral nerve sheath tumors.Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors. I. The role of tumor suppressor mutations.Prognostic implications of p53 protein, epidermal growth factor receptor, and Ki-67 labelling in brain tumoursNeurofibromatosis and childhood leukaemia/lymphoma: a population-based UKCCSG studyMicroRNA-204 critically regulates carcinogenesis in malignant peripheral nerve sheath tumors
P2860
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P2860
Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis.
description
1990 nî lūn-bûn
@nan
1990 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Chromosome 17p deletions and p ...... klinghausen neurofibromatosis.
@ast
Chromosome 17p deletions and p ...... klinghausen neurofibromatosis.
@en
type
label
Chromosome 17p deletions and p ...... klinghausen neurofibromatosis.
@ast
Chromosome 17p deletions and p ...... klinghausen neurofibromatosis.
@en
prefLabel
Chromosome 17p deletions and p ...... klinghausen neurofibromatosis.
@ast
Chromosome 17p deletions and p ...... klinghausen neurofibromatosis.
@en
P2093
P2860
P356
P1476
Chromosome 17p deletions and p ...... klinghausen neurofibromatosis.
@en
P2093
D W Yandell
G E Farmer
J M Whaley
K M Anderson
R N Freiman
V M Riccardi
P2860
P304
P356
10.1073/PNAS.87.14.5435
P407
P577
1990-07-01T00:00:00Z