Assessing the plasticity of DNA target site recognition of the PI-SceI homing endonuclease using a bacterial two-hybrid selection system.
about
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequencesIn vivo selection of engineered homing endonucleases using double-strand break induced homologous recombinationA highly sensitive selection method for directed evolution of homing endonucleases.Engineering a rare-cutting restriction enzyme: genetic screening and selection of NotI variants.Revolutionizing plant biology: multiple ways of genome engineering by CRISPR/CasHoming endonucleases: DNA scissors on a missionThe C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavageCoevolution of a Homing Endonuclease and Its Host Target SequenceRecognition of a common rDNA target site in archaea and eukarya by analogous LAGLIDADG and His-Cys box homing endonucleasesGeneration of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteinsEvolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site SpecificityGene targeting using zinc finger nucleasesAltered target site specificity variants of the I-PpoI His-Cys box homing endonuclease.Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences.The mitochondrial LSU rRNA group II intron of Ustilago maydis encodes an active homing endonuclease likely involved in intron mobility.Determining the specificities of TALENs, Cas9, and other genome-editing enzymesHoming endonucleases: from genetic anomalies to programmable genomic clippersMeganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy.Comprehensive homing endonuclease target site specificity profiling reveals evolutionary constraints and enables genome engineering applications.Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease.Evolution of divergent DNA recognition specificities in VDE homing endonucleases from two yeast species.High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.Targeted approaches for gene therapy and the emergence of engineered meganucleases.Homing endonucleases: from microbial genetic invaders to reagents for targeted DNA modification.Generation of novel nucleases with extended specificity by rational and combinatorial strategies.Towards artificial metallonucleases for gene therapy: recent advances and new perspectives.Generation and analysis of mesophilic variants of the thermostable archaeal I-DmoI homing endonuclease.Genome editing approaches: manipulating of lovastatin and taxol synthesis of filamentous fungi by CRISPR/Cas9 system.Homing endonucleases from mobile group I introns: discovery to genome engineering.Creation of a type IIS restriction endonuclease with a long recognition sequence.Engineering altered protein-DNA recognition specificity.
P2860
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P2860
Assessing the plasticity of DNA target site recognition of the PI-SceI homing endonuclease using a bacterial two-hybrid selection system.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Assessing the plasticity of DN ...... l two-hybrid selection system.
@ast
Assessing the plasticity of DN ...... l two-hybrid selection system.
@en
type
label
Assessing the plasticity of DN ...... l two-hybrid selection system.
@ast
Assessing the plasticity of DN ...... l two-hybrid selection system.
@en
prefLabel
Assessing the plasticity of DN ...... l two-hybrid selection system.
@ast
Assessing the plasticity of DN ...... l two-hybrid selection system.
@en
P2093
P1476
Assessing the plasticity of DN ...... l two-hybrid selection system.
@en
P2093
Carmen M Moure
Frederick S Gimble
Karen L Posey
P304
P356
10.1016/J.JMB.2003.10.013
P407
P577
2003-12-01T00:00:00Z