Automated electrophysiology makes the pace for cardiac ion channel safety screening.
about
Novel screening techniques for ion channel targeting drugsIn silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome.Ion channel screening: advances in technologies and analysis.In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome.HTS techniques for patch clamp-based ion channel screening - advances and economy.New strategies in ion channel screening for drug discovery: are there ways to improve its productivity?hERG inhibitors with similar potency but different binding kinetics do not pose the same proarrhythmic risk: implications for drug safety assessment.An impedance-based cellular assay using human iPSC-derived cardiomyocytes to quantify modulators of cardiac contractility.High-throughput screening of drug-binding dynamics to HERG improves early drug safety assessment.
P2860
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P2860
Automated electrophysiology makes the pace for cardiac ion channel safety screening.
description
2011 nî lūn-bûn
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name
Automated electrophysiology makes the pace for cardiac ion channel safety screening.
@en
Automated electrophysiology makes the pace for cardiac ion channel safety screening.
@nl
type
label
Automated electrophysiology makes the pace for cardiac ion channel safety screening.
@en
Automated electrophysiology makes the pace for cardiac ion channel safety screening.
@nl
prefLabel
Automated electrophysiology makes the pace for cardiac ion channel safety screening.
@en
Automated electrophysiology makes the pace for cardiac ion channel safety screening.
@nl
P2860
P356
P1476
Automated electrophysiology makes the pace for cardiac ion channel safety screening.
@en
P2093
Clemens Möller
Harry Witchel
P2860
P356
10.3389/FPHAR.2011.00073
P577
2011-11-23T00:00:00Z