Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice.
about
SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardationExpression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiationPlacental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouseRetinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesisSignal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylationJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Negative regulation of cytokine signaling and immune responses by SOCS proteinsThe role of suppressors of cytokine signalling in human neoplasmsCytokine signaling in the brain: putting a SOCS in it?Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signalingThe ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signalsSuppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanismsSOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient micePim serine/threonine kinases regulate the stability of Socs-1 proteinDetailed analysis of gene expression during development of T cell lineages in the thymus.Suppressor of cytokine signaling 1 gene expression and polymorphisms in systemic lupus erythematosus.Intracellular delivery of a cell-penetrating SOCS1 that targets IFN-gamma signaling.Expression and functional significance of SOCS-1 and SOCS-3 in astrocytesPolycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1).SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation.Interferons, signal transduction pathways, and the central nervous system.IL-6 transgenic mouse model for extraosseous plasmacytoma.Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STATIL-4 signaling is regulated through the recruitment of phosphatases, kinases, and SOCS proteins to the receptor complex.Crowding-dependent production of colony-stimulating factors by cultured syngeneic or allogeneic hematopoietic cellsA CD4+ T cell antagonist epitope down-regulates activating signaling proteins, up-regulates inhibitory signaling proteins and abrogates HIV-specific T cell function.The paradigm of IL-6: from basic science to medicineSuppressor of cytokine signaling 1 (SOCS1) mitigates anterior uveitis and confers protection against ocular HSV-1 infectionSuppressors of cytokine signalling: SOCS.Regulation of cytokine receptor signaling by SOCS1.Severe pancreatitis with exocrine destruction and increased islet neogenesis in mice with suppressor of cytokine signaling-1 deficiency.Inhibition of SOCS1-/- lethal autoinflammatory disease correlated to enhanced peripheral Foxp3+ regulatory T cell homeostasis.The development of fatal myocarditis and polymyositis in mice heterozygous for IFN-gamma and lacking the SOCS-1 gene.Dysregulation of janus kinases and signal transducers and activators of transcription in cancer.Regulation of TLR signaling and inflammation by SOCS family proteins.Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expressionHost microarray analysis reveals a role for the Salmonella response regulator phoP in human macrophage cell deathSignaling pathways in Th2 development.Regulation of multiple cytokine signalling pathways by SOCS3 is independent of SOCS2.
P2860
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P2860
Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice.
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Accelerated apoptosis of lymph ...... T inhibitor-1) deficient mice.
@ast
Accelerated apoptosis of lymph ...... T inhibitor-1) deficient mice.
@en
type
label
Accelerated apoptosis of lymph ...... T inhibitor-1) deficient mice.
@ast
Accelerated apoptosis of lymph ...... T inhibitor-1) deficient mice.
@en
prefLabel
Accelerated apoptosis of lymph ...... T inhibitor-1) deficient mice.
@ast
Accelerated apoptosis of lymph ...... T inhibitor-1) deficient mice.
@en
P2093
P2860
P356
P1476
Accelerated apoptosis of lymph ...... T inhibitor-1) deficient mice.
@en
P2093
M Fujimoto
M Narazaki
T Kishimoto
T Matsumoto
T Nagasawa
Y Uchiyama
P2860
P304
15577-15582
P356
10.1073/PNAS.95.26.15577
P407
P577
1998-12-01T00:00:00Z