Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.
about
Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in miceRegulation of physiological rates in Caenorhabditis elegans by a tRNA-modifying enzyme in the mitochondriaA mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegansA new member of the family of di-iron carboxylate proteins. Coq7 (clk-1), a membrane-bound hydroxylase involved in ubiquinone biosynthesis.A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicineEvolutionary conservation of drug action on lipoprotein metabolism-related targets.Evidence that ubiquinone is a required intermediate for rhodoquinone biosynthesis in Rhodospirillum rubrum.A Select Subset of Electron Transport Chain Genes Associated with Optic Atrophy Link Mitochondria to Axon Regeneration in Caenorhabditis elegansEvidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans.CLK-1/Coq7p is a DMQ mono-oxygenase and a new member of the di-iron carboxylate protein family.The aging-associated enzyme CLK-1 is a member of the carboxylate-bridged diiron family of proteinsThe paradox of mitochondrial dysfunction and extended longevity.Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase).Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli.Quinones in long-lived clk-1 mutants of Caenorhabditis elegans.Overexpression of peroxisome proliferator-activated receptor gamma co-activator-1alpha leads to muscle atrophy with depletion of ATPPhenotypic and suppressor analysis of defecation in clk-1 mutants reveals that reaction to changes in temperature is an active process in Caenorhabditis elegansDeficiencies in C20 polyunsaturated fatty acids cause behavioral and developmental defects in Caenorhabditis elegans fat-3 mutants.Uncoupling the pleiotropic phenotypes of clk-1 with tRNA missense suppressors in Caenorhabditis elegans.Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis.Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesisAltered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q.Branched-chain amino acids, mitochondrial biogenesis, and healthspan: an evolutionary perspective.Longevity and stress in Caenorhabditis elegansMitochondrial influence on aging rate in Caenorhabditis elegans.Restoring de novo coenzyme Q biosynthesis in Caenorhabditis elegans coq-3 mutants yields profound rescue compared to exogenous coenzyme Q supplementation.The role of stress in ageing: research on the nematode, Caenorhabditis elegans.A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegansAging-associated enzyme human clock-1: substrate-mediated reduction of the diiron center for 5-demethoxyubiquinone hydroxylation.Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans.Mclk1+/- mice are not resistant to the development of atherosclerosis.The SFT-1 and OXA-1 respiratory chain complex assembly factors influence lifespan by distinct mechanisms in C. elegans.Age-dependent changes in mitochondrial morphology and volume are not predictors of lifespan.Molecular genetics of ubiquinone biosynthesis in animals.The Intersection of Aging, Longevity Pathways, and Learning and Memory in C. elegans.Antimicrobial proteins in the response to graphene oxide in Caenorhabditis elegans.A living model for obesity and aging research: Caenorhabditis elegans.The age of heterozygosity.The hypoxia-induced dehydrogenase HorA is required for coenzyme Q10 biosynthesis, azole sensitivity and virulence of Aspergillus fumigatus.Decreased energy metabolism extends life span in Caenorhabditis elegans without reducing oxidative damage.
P2860
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P2860
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.
@ast
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.
@en
type
label
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.
@ast
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.
@en
prefLabel
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.
@ast
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.
@en
P2093
P2860
P356
P1476
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans
@en
P2093
Miyadera H
Murayama K
Sakamoto K
P2860
P304
P356
10.1074/JBC.C000889200
P407
P577
2001-01-17T00:00:00Z