KCNE1 constrains the voltage sensor of Kv7.1 K+ channels. - Wikidata - awgldk - TriplyDB

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

http://www.wikidata.org/entity/Q33327366

about

Distinct subdomains of the KCNQ1 S6 segment determine channel modulation by different KCNE subunits Intracellular domains interactions and gated motions of I(KS) potassium channel subunits The KCNQ1 channel - remarkable flexibility in gating allows for functional versatility KCNQ1 channel modulation by KCNE proteins via the voltage-sensing domain Structural basis of slow activation gating in the cardiac I Ks channel complex Stoichiometry of the KCNQ1 - KCNE1 ion channel complex.Conformational changes of an ion-channel during gating and emerging electrophysiologic properties: Application of a computational approach to cardiac Kv7.1.Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel.KCNE1 remodels the voltage sensor of Kv7.1 to modulate channel function.Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue.Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits.Probing the structural basis for differential KCNQ1 modulation by KCNE1 and KCNE2 Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines.Structural basis for K(V)7.1-KCNE(x) interactions in the I(Ks) channel complex.Gating mechanisms underlying deactivation slowing by two KCNQ1 atrial fibrillation mutations.The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome.The KCNE Tango - How KCNE1 Interacts with Kv7.1.Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels.Photo-Cross-Linking of IKs Demonstrates State-Dependent Interactions between KCNE1 and KCNQ1.Molecular Pathophysiology of Congenital Long QT Syndrome.The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure KCNQ1 channels do not undergo concerted but sequential gating transitions in both the absence and the presence of KCNE1 protein Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels.Steric hindrance between S4 and S5 of the KCNQ1/KCNE1 channel hampers pore opening.

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KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

http://www.wikidata.org/entity/Q33327366

description

2008 nî lūn-bûn

@nan

2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

@ast

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

@en

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

@nl

type

label

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

@ast

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

@en

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

@nl

prefLabel

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

@ast

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

@en

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

@nl

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P1476

KCNE1 constrains the voltage sensor of Kv7.1 K+ channels.

@en

P2093

Asher Peretz

http://www.w3.org/2001/XMLSchema#string

Bernard Attali

http://www.w3.org/2001/XMLSchema#string

Eti Malka

http://www.w3.org/2001/XMLSchema#string

Hella Schottelndreier

http://www.w3.org/2001/XMLSchema#string

Ilanit Yisharel

http://www.w3.org/2001/XMLSchema#string

Liora Shamgar

http://www.w3.org/2001/XMLSchema#string

Yoav Paas

http://www.w3.org/2001/XMLSchema#string

P2860

A constitutively open potassium channel formed by KCNQ1 and KCNE3

The voltage-gated potassium channels and their relatives

KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

KCNQ1 gain-of-function mutation in familial atrial fibrillation

KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

A superfamily of small potassium channel subunits: form and function of the MinK-related peptides (MiRPs).

Neuronal KCNQ potassium channels: physiology and role in disease.

KCNQ potassium channels: physiology, pathophysiology, and pharmacology.

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