Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus
about
Molecular cloning of six novel Krüppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNBLeukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodiesPML, a growth suppressor disrupted in acute promyelocytic leukemiaThe promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma proteinStructure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteinsFusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemiaThe translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNAThe hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in cultureSMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemiaDNA recognition by the aberrant retinoic acid receptors implicated in human acute promyelocytic leukemiaGenomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.Dynamic regulation of Drosophila nuclear receptor activity in vivo.Extramedullary disease in acute promyelocytic leukemia.Acute promyelocytic leukemia: from treatment to genetics and back.Variant-type PML-RAR(alpha) fusion transcript in acute promyelocytic leukemia: use of a cryptic coding sequence from intron 2 of the RAR(alpha) gene and identification of a new clinical subtype resistant to retinoic acid therapy.Transcription therapy for acute promyelocytic leukaemia.Advances in the understanding and management of acute promyelocytic leukemia.Pulsed-field gel electrophoresis analysis of retinoic acid receptor-alpha and promyelocytic leukemia rearrangements. Detection of the t(15;17) translocation in the diagnosis of acute promyelocytic leukemiaThe present status in all-trans retinoic acid (ATRA) treatment for acute promyelocytic leukemia patients: further understanding and comprehensive strategy are required in the future.American Society of Human Genetics presidential address, October 18, 1990Physiological and clinical aspects of vitamin A and its metabolites.RARA and PML genes in acute promyelocytic leukemia.Acute promyelocytic leukaemia.The polymerase chain reaction: its use in the molecular characterization and diagnosis of cancers.Retinoids in cancer treatment.History of acute promyelocytic leukemia: a tale of endless revolutionHeterogeneous nuclear expression of the promyelocytic leukemia (PML) protein in normal and neoplastic human tissues.A hepatitis B virus pre-S-retinoic acid receptor beta chimera transforms erythrocytic progenitor cells in vitroA dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage.Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism.Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networksTerminal differentiation in keratinocytes involves positive as well as negative regulation by retinoic acid receptors and retinoid X receptors at retinoid response elements.Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice.Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia.Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemiaSynergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia.Molecular cloning of a rat chromosome putative recombinogenic sequence homologous to the hepatitis B virus encapsidation signal.t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.RARA fusion genes in acute promyelocytic leukemia: a review.Molecular cytogenetics of the acute promyelocytic leukemia-derived cell line NB4 and of four all-trans retinoic acid-resistant subclones.
P2860
Q22010882-30BD5BAC-AD8B-4728-A6DC-D84ABBAF6294Q24311314-7CCA9F84-7C6B-40DA-A277-4AFA0A52DEF5Q24324168-58B05D1B-6DEF-45A5-AF38-F4F4F1DD2FD9Q24324766-CACC86C6-E853-422F-A497-DF6E602AD305Q24555702-E18014E6-ABF9-4EC3-A93A-505517E2CE53Q24564693-3D52C14C-A0F6-435D-B3EE-6896EC45E0F6Q24606378-6609FF2A-B2EA-457A-B748-56BB7A2DEC02Q24632107-6780753B-E2C8-41C7-9D03-82DD15E5EDFAQ24653689-81C2E08E-ACB7-4303-B730-AA968102A3D1Q28359892-8FA66270-EC05-48DB-A58A-CDD9BF8347EAQ30982911-733DECBA-8B43-4965-B226-EC317B10977DQ33254273-FD0A180F-D48C-45C8-AEAC-5B5D4758A0EFQ33604339-21D902D2-86FF-4ADC-837A-F7D793C72456Q33739256-1DC0607C-6D8F-4419-AFA5-7D92883FF670Q34064907-93E3737F-7D78-409F-BC52-AA4E7BEFA703Q34074712-00D462BB-4BCE-4676-91E8-5B0946CDB651Q34680944-77B90091-4E74-46EE-AC5F-84898BA41E45Q34728496-21D888F1-470F-4E24-A343-A8073AC92166Q35196474-72125BA0-EF89-4008-9EEF-F742A296FF62Q35197031-BB09202C-0C91-469B-8A1A-51B8DEF4B1EDQ35238200-E36F9329-D4A0-4285-BB28-9DA042EB1214Q35239243-33C71361-CCD4-41D1-99BE-FF734F4AF0ECQ35358604-9F3D3991-1B3D-4644-8348-12EBDEE196C9Q35367235-C439E863-D954-4DE8-AC1D-8ADEBBC86760Q35536280-A6826E8D-3F92-48DD-A75C-86470E1359BAQ35640780-4ADC80E2-DEFA-4376-AC72-11DBE21223B3Q35782722-FB8A54C9-7B5F-42B6-9419-A875C853C905Q36029147-65D861A3-6BF6-4421-B0DE-F472F0404B81Q36452885-DF3B8541-3649-433C-9B1F-448A8E2072A2Q36566818-9D7E4C7B-BC95-4E49-96EC-DF1DB6DBC382Q36570690-8FEAB07F-0E0A-4667-9265-157D93BF4CC7Q36704336-1AAE56E6-E06D-4581-AA30-60D1D46A0275Q36771988-45626DC3-6DAE-484C-A3A9-91AFAF84F5C2Q36916496-11B4AA99-6095-4E3B-BBDB-E2C99034C257Q37031781-7F7A5770-6A64-4B1A-873D-5EAF73E9619BQ37397791-6F9402AC-F151-4B73-BF26-5EA7DE8876D1Q37500680-A5050C7E-BBB0-4654-BFE5-0DE7D9F8E912Q37627380-D8DBA73A-F87C-4FA2-ACAB-9C022FAA842CQ38203568-0B038B93-3153-4372-96F6-8CA913BD7F00Q38487393-8D81CD70-EB92-416A-AA1D-7B2F6616E94E
P2860
Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus
description
1991 nî lūn-bûn
@nan
1991 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի մարտին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Translocation breakpoint of ac ...... noic acid receptor alpha locus
@ast
Translocation breakpoint of ac ...... noic acid receptor alpha locus
@en
Translocation breakpoint of ac ...... oic acid receptor alpha locus.
@nl
type
label
Translocation breakpoint of ac ...... noic acid receptor alpha locus
@ast
Translocation breakpoint of ac ...... noic acid receptor alpha locus
@en
Translocation breakpoint of ac ...... oic acid receptor alpha locus.
@nl
prefLabel
Translocation breakpoint of ac ...... noic acid receptor alpha locus
@ast
Translocation breakpoint of ac ...... noic acid receptor alpha locus
@en
Translocation breakpoint of ac ...... oic acid receptor alpha locus.
@nl
P2093
P2860
P356
P1476
Translocation breakpoint of ac ...... noic acid receptor alpha locus
@en
P2093
Giacomucci A
Mencarelli A
Pandolfi PP
Rambaldi A
Zangrilli D
P2860
P304
P356
10.1073/PNAS.88.5.1977
P407
P577
1991-03-01T00:00:00Z