Completion of a Programmable DNA-Binding Small Molecule Library - Wikidata - awgldk - TriplyDB

Completion of a Programmable DNA-Binding Small Molecule Library

Completion of a Programmable DNA-Binding Small Molecule Library

http://www.wikidata.org/entity/Q33348532

about

Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma Allosteric modulation of DNA by small molecules Structural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor Binding Conformationally rigid proteomimetics: a case study in designing antimicrobial aryl oligomers.Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.Modifications at the C-terminus to improve pyrrole-imidazole polyamide activity in cell culture.A novel polyamide SL-A92 as a potential fungal resistance blocker: synthesis and bioactivities in Candida albicans.Binding studies of a large antiviral polyamide to a natural HPV sequence.Mini review: protein-protein interactions in transcription: a fertile ground for helix mimetics.DNA-binding small molecules as inhibitors of transcription factors.Noncanonical mechanisms to regulate nuclear receptor signaling.Tumor xenograft uptake of a pyrrole-imidazole (Py-Im) polyamide varies as a function of cell line grafted.Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.Synthesis of cyclic Py-Im polyamide libraries.DNA sequence selectivity of hairpin polyamide turn units Quantitative microarray profiling of DNA-binding molecules Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove binders Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns.Pharmacokinetics of Py-Im polyamides depend on architecture: cyclic versus linear.Alpha-diaminobutyric acid-linked hairpin polyamides.Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice.Gene expression changes in a tumor xenograft by a pyrrole-imidazole polyamide.Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography.RecA-mediated strand invasion of DNA by oligonucleotides substituted with 2-aminoadenine and 2-thiothymine.Cyclic pyrrole-imidazole polyamides targeted to the androgen response element.Solution-phase synthesis of pyrrole-imidazole polyamides Quantitative detection of small molecule/DNA complexes employing a force-based and label-free DNA-microarray.Oligomerization route to Py-Im polyamide macrocycles.Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif Pentamidine reverses the splicing defects associated with myotonic dystrophy.An HRE-Binding Py-Im Polyamide Impairs Hypoxic Signaling in Tumors.Comparative Analysis of DNA-Binding Selectivity of Hairpin and Cyclic Pyrrole-Imidazole Polyamides Based on Next-Generation Sequencing.Efficient Synthesis of Peptide and Protein Functionalized Pyrrole-Imidazole Polyamides Using Native Chemical Ligation.Binding of hairpin pyrrole and imidazole polyamides to DNA: relationship between torsion angle and association rate constants.Modulation of DNA-polyamide interaction by β-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics.Pyrrole-imidazole polyamides distinguish between double-helical DNA and RNA.An overview of recent advances in duplex DNA recognition by small molecules.

P2860

Q24669875-1FC57B11-2D11-40A8-A864-1024A77B89AD Q26780141-66D14198-13E1-49C5-9A78-6339D88B3E94 Q27656940-0C72228A-B01A-4D57-AC04-F7784896F18A Q27664249-18C4708F-5605-4149-9D11-7439B0A51E4A Q30367362-4FEC7DF2-AF92-46DF-A702-2E3B9993E536 Q33331950-76A6CC27-87CA-49C7-9641-FF529EF51B6E Q33477522-6B05F7A1-19A9-4122-8E6F-6FC351CFBBCD Q33557539-08EDB5CE-96BC-4C40-B6E2-3F14A751FAE1 Q33717554-83E79990-C2B6-47DF-A975-A2791A951942 Q34253106-7B9D63A4-8435-486F-B1D5-1E01E86A42C8 Q34253203-65E4159B-28BB-4FD1-AB48-FEECD7FFB11D Q34338685-E1D92D47-4295-440C-A446-C5EEE8065AAB Q34394131-5B80A62A-FAD0-4A02-808C-D1CBC548E923 Q34421960-716E51E1-ACA0-4482-BDCE-303E4F9E7B6E Q34459196-2021F4C8-DE20-45C5-B958-125B777FEC33 Q34708077-4AC26680-4743-4AE1-8BD5-E02D9455A6B6 Q34732038-429A6E2E-21BE-4525-8AF6-476489771599 Q35709298-BD5E960B-ED8F-4886-AF9A-EEB2FC4B34B7 Q35823735-88D7F36F-90B6-40F7-81F9-5F8D33582950 Q35949095-352153B7-D179-45BA-B52A-F079DD40652C Q36275137-32CD27DE-BA99-437F-B48E-3F307551CAEC Q36275422-8D878B39-B4E1-4828-A6BE-B6A24F061AB3 Q36342812-B6710F88-F309-48AA-ACCD-88CFEC7F06C6 Q36749396-5202F6B9-EB75-4A4B-BE78-8C6C46E5D4BB Q36861667-A942DC32-60C7-4B24-A211-1D4619FF62D8 Q36986752-036FACF2-4BED-4E57-A7A3-0D4AC303D050 Q37209293-CA1DDCDB-71AD-4C14-BBD2-A8156058E760 Q37209301-6D6E3A98-C833-42C1-A733-01BF80D57626 Q37263696-CD25E91B-C476-481D-9446-942A692560B7 Q37329318-69600A27-8F08-4D97-980A-21A2B5E32196 Q37348402-F4E9B1F3-2407-4C0C-99FD-851AA95160D0 Q37398257-12737CE0-E253-480E-A873-BC53A9529052 Q37413602-BE5AA680-E28C-43F3-A36A-A4A54F44484C Q38807563-FE403C03-BD22-4423-9240-80F94EC38F02 Q39624806-3CBE44A9-2307-4263-A6D8-C308C49E7ACD Q41456295-87A9F4EE-6891-4A67-8D7C-2FB60AAAFF22 Q41911133-4EEEB2A6-B7B9-411B-92C6-679086D15D8D Q42125210-5CF46905-8C36-4D84-9DED-09966C9C9827 Q42217171-0F619926-398C-44B1-8E33-6BDA01C0BCE5 Q55476273-80183CA0-2051-4273-9DFD-AE9C067B8C5E

P2860

Completion of a Programmable DNA-Binding Small Molecule Library

http://www.wikidata.org/entity/Q33348532

description

2007 nî lūn-bûn

@nan

2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Completion of a Programmable DNA-Binding Small Molecule Library

@ast

Completion of a Programmable DNA-Binding Small Molecule Library

@en

type

label

Completion of a Programmable DNA-Binding Small Molecule Library

@ast

Completion of a Programmable DNA-Binding Small Molecule Library

@en

prefLabel

Completion of a Programmable DNA-Binding Small Molecule Library

@ast

Completion of a Programmable DNA-Binding Small Molecule Library

@en

P1433

Q33348532-C9A70F84-5AD4-4E88-8FD2-126FA8B20472

P1476

Q33348532-FA7418E3-E3ED-40AE-8DFD-09B1E18DB157

P2093

Q33348532-27C9DE83-C6E3-42ED-B7B0-76185771AAFB

Q33348532-28987DC4-683E-4D9B-9883-BE69D7BEAD86

Q33348532-6852B1A7-C096-4473-95BF-633C62864444

Q33348532-6A3B728B-4087-4EBA-9095-65E9B1AE5346

Q33348532-6B918DCA-F9E1-4DBE-AE87-5FEA1D48F102

Q33348532-9E35A9B0-E78A-4F7E-9CC1-920BE6DBCC6B

Q33348532-A34817AD-1BEA-4C67-B13D-F79EB204B727

Q33348532-AA505D70-4767-4629-B5F5-E835857F8219

Q33348532-C04A7BE1-03AA-4E84-BC32-193608D64F6C

P2860

Q33348532-12EA2A96-9A8B-4339-AADA-669B722DA84C

Q33348532-138268DE-E93A-4FE7-8F8F-567B467CCE86

Q33348532-164C3890-FE9E-474C-85DC-768D62570533

Q33348532-2E8FE8D4-CA46-4BFD-8B8B-43768B695289

Q33348532-3BB509DD-F25C-447A-900C-B9F4A90F207F

Q33348532-408023D8-CEF3-497F-A2B2-2418EED42323

Q33348532-4757B742-4F12-466F-B3D6-7B404702DE27

Q33348532-525BA512-4B57-483A-92B1-A5FBD216114A

Q33348532-5C3C0771-FD49-4C17-9DA5-124E528E871C

Q33348532-5E33E4AC-E453-4BC2-BA21-F2AC886FDB78

P304

Q33348532-5BAFCD22-F4F5-478D-8ABC-EA8A395602CB

P31

Q33348532-90EC7340-4031-4D0F-AF78-D20EB06F4AB6

P356

Q33348532-4DD5C2EB-8C9E-4F38-B204-A063D90CA3A8

P433

Q33348532-0B7CB1EA-6208-4ED6-9052-798E9365C275

P478

Q33348532-E753FFFA-B459-47BE-B932-E02E6588AD26

P50

Q33348532-FB451C6A-3228-4093-8FA4-0B22F3A4BC4F

P577

Q33348532-73B2DE7A-A806-4B17-88A1-1302C31083FD

P5875

Q33348532-0FE48F24-303A-4B43-8C32-E1E872786E25

P698

Q33348532-2631C361-71F6-4685-8FF1-CFD31A413193

P932

Q33348532-0E619B1D-6EDA-4133-BCCC-E8C295B733EB

P356

J.TET.2007.03.041

P1433

P1476

Completion of a Programmable DNA-Binding Small Molecule Library

@en

P2093

Alexander Heckel

http://www.w3.org/2001/XMLSchema#string

Bogdan Z Olenyuk

http://www.w3.org/2001/XMLSchema#string

Carey F Hsu

http://www.w3.org/2001/XMLSchema#string

Clay C C Wang

http://www.w3.org/2001/XMLSchema#string

James W Puckett

http://www.w3.org/2001/XMLSchema#string

Jason M Belitsky

http://www.w3.org/2001/XMLSchema#string

John W Phillips

http://www.w3.org/2001/XMLSchema#string

John W Trauger

http://www.w3.org/2001/XMLSchema#string

Michelle E Farkas

http://www.w3.org/2001/XMLSchema#string

P2860

Structural basis for G.C recognition in the DNA minor groove

A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA

Sequencing end-labeled DNA with base-specific chemical cleavages

Recognition of the DNA minor groove by pyrrole-imidazole polyamides

Targeted derepression of the human immunodeficiency virus type 1 long terminal repeat by pyrrole-imidazole polyamides.

Molecular recognition of DNA by small molecules

Regulation of gene expression by small molecules

Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands

Recognition of DNA by designed ligands at subnanomolar concentrations

Specific targeting of insect and vertebrate telomeres with pyrrole and imidazole polyamides

P304

6146-6151

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.TET.2007.03.041

http://www.w3.org/2001/XMLSchema#string

P433

27

http://www.w3.org/2001/XMLSchema#string

P478

63

http://www.w3.org/2001/XMLSchema#string

P50

P577

2007-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5256186

http://www.w3.org/2001/XMLSchema#string

P698

18596841

http://www.w3.org/2001/XMLSchema#string

P932

2151752

http://www.w3.org/2001/XMLSchema#string