Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
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The Discovery of Novel Biomarkers Improves Breast Cancer Intrinsic Subtype Prediction and Reconciles the Labels in the METABRIC Data Set.The mTOR inhibitor rapamycin synergizes with a fatty acid synthase inhibitor to induce cytotoxicity in ER/HER2-positive breast cancer cellsAnastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway.Poly (A)+ transcriptome assessment of ERBB2-induced alterations in breast cell lines.Long-range massively parallel mate pair sequencing detects distinct mutations and similar patterns of structural mutability in two breast cancer cell linesMiR-99a antitumor activity in human breast cancer cells through targeting of mTOR expression.Cancer in silico drug discovery: a systems biology tool for identifying candidate drugs to target specific molecular tumor subtypesAdhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progressionCytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer.HGUE-C-1 is an atypical and novel colon carcinoma cell line.Multiple gene aberrations and breast cancer: lessons from super-responders.Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancerP-mTOR Expression and Implication in Breast Carcinoma: A Systematic Review and Meta-AnalysisPhosphorylated mTOR expression correlates with poor outcome in early-stage triple negative breast carcinomasTranscriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation.TCTP is an androgen-regulated gene implicated in prostate cancer.Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells.AKT/mTOR substrate P70S6K is frequently phosphorylated in gallbladder cancer tissue and cell lines.Characterization of the DNA copy-number genome in the blood of cutaneous T-cell lymphoma patients.Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance.Global identification of genes and pathways regulated by Akt during activation of T helper cells.Regulation of the SREBP transcription factors by mTORC1.Novel therapeutic strategy for breast cancer: mammalian target of rapamycin inhibition.Identification of Downstream Genes of the mTOR Pathway that Predict Recurrence and Progression in Non-Muscle Invasive High-Grade Urothelial Carcinoma of the Bladder.Breast cancer tissue slices as a model for evaluation of response to rapamycin.Quantitative phosphoproteomic analysis reveals system-wide signaling pathways regulated by site-specific phosphorylation of Keratin-8 in skin squamous cell carcinoma derived cell line.Neferine induces autophagy of human ovarian cancer cells via p38 MAPK/ JNK activation.Potential targeting of B7-H4 for the treatment of cancer.Neferine attenuates the protein level and toxicity of mutant huntingtin in PC-12 cells via induction of autophagy.Chemical Inhibitors and microRNAs (miRNA) Targeting the Mammalian Target of Rapamycin (mTOR) Pathway: Potential for Novel Anticancer Therapeutics.Expression of mTOR/70S6K signaling pathway in pathological scar fibroblasts and the effects of resveratrol intervention.miR-195 Regulates Proliferation and Apoptosis through Inhibiting the mTOR/p70s6k Signaling Pathway by Targeting HMGA2 in Esophageal Carcinoma Cells.Targeting Aberrant p70S6K Activation for Estrogen Receptor-Negative Breast Cancer Prevention.Monitoring of neuronal loss in the hippocampus of Aβ-injected rat: autophagy, mitophagy, and mitochondrial biogenesis stand against apoptosis.H2S protects hippocampal neurons from anoxia-reoxygenation through cAMP-mediated PI3K/Akt/p70S6K cell-survival signaling pathways.p70 Ribosomal protein S6 kinase (Rps6kb1): an update.Prucalopride inhibits the glioma cells proliferation and induces autophagy via AKT-mTOR pathway.DECtp: Calling Differential Gene Expression Between Cancer and Normal Samples by Integrating Tumor Purity Information
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P2860
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
@ast
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
@en
type
label
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
@ast
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
@en
prefLabel
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
@ast
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
@en
P2093
P2860
P356
P1433
P1476
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
@en
P2093
Anni Nieminen
Henna Heinonen
Juha Klefström
Matti Saarela
Outi Monni
P2860
P2888
P356
10.1186/1471-2164-9-348
P407
P577
2008-07-24T00:00:00Z
P5875
P6179
1050501385