Transcriptome analysis of synaptoneurosomes identifies neuroplasticity genes overexpressed in incipient Alzheimer's disease. - Wikidata - awgldk - TriplyDB

Transcriptome analysis of synaptoneurosomes identifies neuroplasticity genes overexpressed in incipient Alzheimer's disease.

Transcriptome analysis of synaptoneurosomes identifies neuroplasticity genes overexpressed in incipient Alzheimer's disease.

http://www.wikidata.org/entity/Q33419370

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Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice Degradation of high affinity HuD targets releases Kv1.1 mRNA from miR-129 repression by mTORC1 EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.RNA-Seq data mining: downregulation of NeuroD6 serves as a possible biomarker for alzheimer's disease brains.Transcriptome analyses identify key cellular factors associated with HIV-1-associated neuropathogenesis in infected men.Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer's disease.Regulation of protein levels in subcellular domains through mRNA transport and localized translation.Proteinase-activated receptor-2 up-regulation by Fcgamma-receptor activation in human neutrophils Astrocyte-neuron lactate transport is required for long-term memory formation.Altered distribution of the EphA4 kinase in hippocampal brain tissue of patients with Alzheimer's disease correlates with pathology Membrane progesterone receptors (mPRs) mediate progestin induced antimorbidity in breast cancer cells and are expressed in human breast tumors.Concerted perturbation observed in a hub network in Alzheimer's disease Exercise modifies α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor expression in striatopallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse.Inverse correlation between Alzheimer's disease and cancer: implication for a strong impact of regenerative propensity on neurodegeneration?Profiling axonal mRNA transport.Parallel age-associated changes in brain and plasma neuronal pentraxin receptor levels in a transgenic APP/PS1 rat model of Alzheimer's disease.AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly Amyloid-β(25-35) Modulates the Expression of GirK and KCNQ Channel Genes in the Hippocampus.Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex.Network Comparison of Inflammation in Colorectal Cancer and Alzheimer's Disease.Applying the new genomics to alcohol dependence.Proteogenomics of synaptosomal mitochondrial oxidative stress.Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment.Genome-wide approaches to dissect the roles of RNA binding proteins in translational control: implications for neurological diseases Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease.Glutamate system, amyloid ß peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment.Towards the Molecular Foundations of Glutamatergic-targeted Antidepressants.Eph receptors and ephrins in neuron-astrocyte communication at synapses.Gene expression profiling in human neurodegenerative disease.Pathway analysis of the human brain transcriptome in disease.Rare Variants and Transcriptomics in Alzheimer disease.Reversing synapse loss in Alzheimer's disease: Rho-guanosine triphosphatases and insights from other brain disorders.Dissecting Complex and Multifactorial Nature of Alzheimer's Disease Pathogenesis: a Clinical, Genomic, and Systems Biology Perspective.EphA4 is Involved in Sleep Regulation but Not in the Electrophysiological Response to Sleep Deprivation.DENN/MADD/IG20 alternative splicing changes and cell death in Alzheimer's disease.Integrating the Alzheimer's disease proteome and transcriptome: a comprehensive network model of a complex disease.Transcriptional signatures mediated by acetylation overlap with early-stage Alzheimer's disease.

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P2860

Transcriptome analysis of synaptoneurosomes identifies neuroplasticity genes overexpressed in incipient Alzheimer's disease.

http://www.wikidata.org/entity/Q33419370

description

2009 nî lūn-bûn

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年論文

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2009年論文

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2009年論文

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Transcriptome analysis of syna ...... incipient Alzheimer's disease.

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Transcriptome analysis of syna ...... incipient Alzheimer's disease.

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Transcriptome analysis of syna ...... incipient Alzheimer's disease.

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Transcriptome analysis of syna ...... incipient Alzheimer's disease.

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Transcriptome analysis of syna ...... incipient Alzheimer's disease.

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Transcriptome analysis of syna ...... incipient Alzheimer's disease.

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Transcriptome analysis of syna ...... incipient Alzheimer's disease.

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Bryan Spann

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Carol A Miller

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Carol McCleary

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Celia Williams

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Ruty Mehrian Shai

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Traci Sitzer

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Ya-Hsuan Hsu

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Yi Mo

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Yongchun Wu

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P2860

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

Neuropathological stageing of Alzheimer-related changes

Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homer1a

Translational control by CPEB: a means to the end

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10.1371/JOURNAL.PONE.0004936

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neuroplasticity

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2654156

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