Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease.
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From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug designSevere Acute Respiratory Syndrome Coronavirus Papain-like Novel Protease Inhibitors: Design, Synthesis, Protein−Ligand X-ray Structure and Biological EvaluationX-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like ProteasesStructural view and substrate specificity of papain-like protease from avian infectious bronchitis virus.The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.Challenges and opportunities for new protein crystallization strategies in structure-based drug design.Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus.Synergistic inhibitor binding to the papain-like protease of human SARS coronavirus: mechanistic and inhibitor design implications.Comparison of SARS and NL63 papain-like protease binding sites and binding site dynamics: inhibitor design implicationsInhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoVUbiquitin-specific proteases as cancer drug targets.Recent progress in the discovery of inhibitors targeting coronavirus proteases.Targeting deubiquitinase USP28 for cancer therapy.Stereoselective Ketone Rearrangements with Hypervalent Iodine Reagents.
P2860
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P2860
Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease.
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structure-based design, synthe ...... onavirus papain-like protease.
@ast
Structure-based design, synthe ...... onavirus papain-like protease.
@en
type
label
Structure-based design, synthe ...... onavirus papain-like protease.
@ast
Structure-based design, synthe ...... onavirus papain-like protease.
@en
prefLabel
Structure-based design, synthe ...... onavirus papain-like protease.
@ast
Structure-based design, synthe ...... onavirus papain-like protease.
@en
P2093
P2860
P356
P1476
Structure-based design, synthe ...... onavirus papain-like protease.
@en
P2093
Arun K Ghosh
Bellur S Prabhakar
Daniel B Nichols
Debbie C Mulhearn
Jun Takayama
Katrina Sleeman
Kiira Ratia
Melissa Coughlin
Michael E Johnson
Rima Chaudhuri
P2860
P304
P356
10.1021/JM900611T
P407
P577
2009-08-01T00:00:00Z