IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.
about
A20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activityTumor suppressor PDCD4 inhibits NF-κB-dependent transcription in human glioblastoma cells by direct interaction with p65Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasisIKKα contributes to canonical NF-κB activation downstream of Nod1-mediated peptidoglycan recognitionEndocytosis-independent function of clathrin heavy chain in the control of basal NF-κB activationNLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signalingTranslocator Protein-Mediated Stabilization of Mitochondrial Architecture during Inflammation Stress in Colonic CellsNF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs.Distinct motifs in the intracellular domain of human CD30 differentially activate canonical and alternative transcription factor NF-κB signalingGenistein sensitizes bladder cancer cells to HCPT treatment in vitro and in vivo via ATM/NF-κB/IKK pathway-induced apoptosis.Exogenous signal-independent nuclear IkappaB kinase activation triggered by Nkx3.2 enables constitutive nuclear degradation of IkappaB-alpha in chondrocytes.Functional interrelationship between the WASF3 and KISS1 metastasis-associated genes in breast cancer cells.C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction.EBV LMP1: New and shared pathways to NF-κB activation.Genome-wide siRNA screen for mediators of NF-κB activationActivation of IKK/NF-κB provokes renal inflammatory responses in guanylyl cyclase/natriuretic peptide receptor-A gene-knockout mice.Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic ratsCooperation between classical and alternative NF-κB pathways regulates proinflammatory responses in epithelial cells.TNF-α Modulation of Intestinal Tight Junction Permeability Is Mediated by NIK/IKK-α Axis Activation of the Canonical NF-κB Pathway.Regulation of anoikis by deleted in breast cancer-1 (DBC1) through NF-κB.Noncanonical NF-κB signaling is limited by classical NF-κB activity.IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1.Progesterone and calcitriol attenuate inflammatory cytokines CXCL1 and CXCL2 in ovarian and endometrial cancer cells.CITED2 Modulates Breast Cancer Metastatic Ability through Effects on IKKα.Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF-κB and Downregulation of COX-2/iNOS.IKKβ-induced inflammation impacts the kinetics but not the magnitude of the immune response to a viral vector.Doxorubicin-induced activation of NF-κB in melanoma cells is abrogated by inhibition of IKKβ, but not by a novel IKKα inhibitor.Activation of proMMP-2 by U46619 occurs via involvement of p(38)MAPK-NFκB-MT1MMP signaling pathway in pulmonary artery smooth muscle cells.Activation of NF-kB-Mediated TNF-Induced Antimicrobial Immunity Is Required for the Efficient Brucella abortus Clearance in RAW 264.7 Cells.Tumor necrosis factor-α-induced nuclear factor-kappaB activation in human cardiomyocytes is mediated by NADPH oxidase.Discovery of novel potent nuclear factor kappa-B inhibitors (IKK-β) via extensive ligand-based modeling and virtual screening.Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis.The small-molecule inhibitor selectivity between IKKα and IKKβ kinases in NF-κB signaling pathway.Targeting IKKβ in Cancer: Challenges and Opportunities for the Therapeutic Utilisation of IKKβ Inhibitors
P2860
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P2860
IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
IKKalpha and IKKbeta each func ...... TNF-induced/canonical pathway.
@ast
IKKalpha and IKKbeta each func ...... TNF-induced/canonical pathway.
@en
IKKalpha and IKKbeta each func ...... TNF-induced/canonical pathway.
@nl
type
label
IKKalpha and IKKbeta each func ...... TNF-induced/canonical pathway.
@ast
IKKalpha and IKKbeta each func ...... TNF-induced/canonical pathway.
@en
IKKalpha and IKKbeta each func ...... TNF-induced/canonical pathway.
@nl
prefLabel
IKKalpha and IKKbeta each func ...... TNF-induced/canonical pathway.
@ast
IKKalpha and IKKbeta each func ...... TNF-induced/canonical pathway.
@en
IKKalpha and IKKbeta each func ...... TNF-induced/canonical pathway.
@nl
P2093
P2860
P1433
P1476
IKKalpha and IKKbeta each func ...... TNF-induced/canonical pathway.
@en
P2093
Albert S Baldwin
Evan Merkhofer
Mazhar Adli
Patricia Cogswell
P2860
P356
10.1371/JOURNAL.PONE.0009428
P407
P577
2010-02-25T00:00:00Z