A lethal myeloproliferative syndrome in mice transplanted with bone marrow cells infected with a retrovirus expressing granulocyte-macrophage colony stimulating factor.
about
Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factorGranulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathologyThe tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox proteinPhosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicityPivotal roles of GM-CSF in autoimmunity and inflammationRegulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life spanTransplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus.Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation.Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.Expression of human alpha-globin and mouse/human hybrid beta-globin genes in murine hemopoietic stem cells transduced by recombinant retroviruses.Low-affinity placenta-derived receptors for human granulocyte-macrophage colony-stimulating factor can deliver a proliferative signal to murine hemopoietic cells.Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia.Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes.bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.The truncation that generated the v-cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation.Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukemic cells in vitroRetroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures.Fatal syndrome in mice engrafted with cells producing high levels of the leukemia inhibitory factor.Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cellsA knock-in Npm1 mutation in mice results in myeloproliferation and implies a perturbation in hematopoietic microenvironmentLong-term exposure to retrovirally expressed granulocyte-colony-stimulating factor induces a nonneoplastic granulocytic and progenitor cell hyperplasia without tissue damage in miceOverexpression of protein kinase C-{epsilon} in the mouse epidermis leads to a spontaneous myeloproliferative-like disease.Isolation of new oncogenic forms of the murine c-fms gene.The potential role of recombinant hematopoietic colony-stimulating factors in preventing infections in the immunocompromised hostThe colony-stimulating factors and cancer.Transgenic mice in the study of cytokine functionThe Shc-binding site of the betac subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesisAbrogation of the requirement for feeder cell interaction and T cell receptor stimulation of lymphocytes infected with retroviral vectors.Expression cloning of oncogenes by retroviral transfer of cDNA libraries.A simple and efficient procedure for generating stable expression libraries by cDNA cloning in a retroviral vector.A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells.Murine pluripotent hematopoietic progenitors constitutively expressing a normal erythropoietin receptor proliferate in response to erythropoietin without preferential erythroid cell differentiation.Hyperexpression of interleukin-7 is not necessary or sufficient for transformation of a pre-B lymphoid cell line.High-efficiency identification of genes by functional analysis from a retroviral cDNA expression library.Leukemia initiated by hemopoietic stem cells expressing the v-abl oncogene.Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene.Determinants of eosinophil survival and apoptotic cell death.Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions.Promoter interactions in retrovirus vectors introduced into fibroblasts and embryonic stem cells.
P2860
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P2860
A lethal myeloproliferative syndrome in mice transplanted with bone marrow cells infected with a retrovirus expressing granulocyte-macrophage colony stimulating factor.
description
1989 nî lūn-bûn
@nan
1989 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
A lethal myeloproliferative sy ...... age colony stimulating factor.
@ast
A lethal myeloproliferative sy ...... age colony stimulating factor.
@en
A lethal myeloproliferative sy ...... age colony stimulating factor.
@nl
type
label
A lethal myeloproliferative sy ...... age colony stimulating factor.
@ast
A lethal myeloproliferative sy ...... age colony stimulating factor.
@en
A lethal myeloproliferative sy ...... age colony stimulating factor.
@nl
prefLabel
A lethal myeloproliferative sy ...... age colony stimulating factor.
@ast
A lethal myeloproliferative sy ...... age colony stimulating factor.
@en
A lethal myeloproliferative sy ...... age colony stimulating factor.
@nl
P2093
P2860
P1433
P1476
A lethal myeloproliferative sy ...... age colony stimulating factor.
@en
P2093
G R Johnson
I K Hariharan
P2860
P304
P407
P50
P577
1989-02-01T00:00:00Z