Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.
about
P1343
Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors.Targeted and highly efficient gene transfer into CD4+ cells by a recombinant human immunodeficiency virus retroviral vector.Retroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures.Gene therapy: here to stay.Replication-competent lentivirus analysis of clinical grade vector products.Gene transfer into hematopoietic stem cells: long-term maintenance of in vitro activated progenitors without marrow ablation.Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector.A chromatin insulator protects retrovirus vectors from chromosomal position effects.Inhibition of clinical human immunodeficiency virus (HIV) type 1 isolates in primary CD4+ T lymphocytes by retroviral vectors expressing anti-HIV genes.An array of murine leukemia virus-related elements is transmitted and expressed in a primate recipient of retroviral gene transfer.Retroviral transduction of a mutant methylguanine DNA methyltransferase gene into human CD34 cells confers resistance to O6-benzylguanine plus 1,3-bis(2-chloroethyl)-1-nitrosourea.Targeted expansion of genetically modified bone marrow cells.Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transferIsolation of genetic suppressor elements, inducing resistance to topoisomerase II-interactive cytotoxic drugs, from human topoisomerase II cDNARetroviral vector production in the National Gene Vector Laboratory at Indiana University.Gaucher disease as a paradigm of current issues regarding single gene mutations of humansHuman cord blood cells as targets for gene transfer: potential use in genetic therapies of severe combined immunodeficiency disease.PML suppresses oncogenic transformation of NIH/3T3 cells by activated neu.Recent advances in the growth and isolation of primitive human haemopoietic progenitor cells.Peripheral blood progenitors as a target for genetic correction of p47phox-deficient chronic granulomatous diseaseCharacterization of replication-competent retroviruses from nonhuman primates with virus-induced T-cell lymphomas and observations regarding the mechanism of oncogenesis.Production of high-titer helper virus-free retroviral vectors by cocultivation of packaging cells with different host ranges.Ectopic lymphokine gene expression in human peripheral blood lymphocytes in vivo.Expression of the gibbon ape leukemia virus receptor-1 in rhesus macaque tissues.Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vectorLong-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells.Development of gene therapy: potential in severe combined immunodeficiency due to adenosine deaminase deficiency.Improved retroviral gene transfer into murine and Rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor.Expression of a swine class II gene in murine bone marrow hematopoietic cells by retroviral-mediated gene transfer.Vector-mediated Tum-5 expression in neovascular endothelial cells for treating hepatocellular carcinoma.Screening retroviral packaging cells for highly efficient virus production by using a combined selection procedure.A new retrovirus packaging cell for gene transfer constructed from amplified long terminal repeat-free chimeric proviral genes.Use of the hereditary persistence of fetal hemoglobin 2 enhancer to increase the expression of oncoretrovirus vectors for human gamma-globin.Amplified and tissue-directed expression of retroviral vectors using ping-pong techniques.Retroviral transduction of quiescent haematopoietic cells using a packaging cell line expressing the membrane-bound form of stem cell factor.Absence of Replication-Competent Lentivirus in the Clinic: Analysis of Infused T Cell Products.Increased resistance to nitrogen mustards and antifolates following in vitro selection of murine fibroblasts and primary hematopoietic cells transduced with a bicistronic retroviral vector expressing the rat glutathione S-transferase A3 and a mutantDifferences among nonhuman primates in susceptibility to bone marrow progenitor transduction with retrovirus vectors.Screening Clinical Cell Products for Replication Competent Retrovirus: The National Gene Vector Biorepository Experience
P2860
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P2860
Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.
description
1990 nî lūn-bûn
@nan
1990 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Development of a high-titer re ...... nkey hematopoietic stem cells.
@ast
Development of a high-titer re ...... nkey hematopoietic stem cells.
@en
Development of a high-titer re ...... nkey hematopoietic stem cells.
@nl
type
label
Development of a high-titer re ...... nkey hematopoietic stem cells.
@ast
Development of a high-titer re ...... nkey hematopoietic stem cells.
@en
Development of a high-titer re ...... nkey hematopoietic stem cells.
@nl
prefLabel
Development of a high-titer re ...... nkey hematopoietic stem cells.
@ast
Development of a high-titer re ...... nkey hematopoietic stem cells.
@en
Development of a high-titer re ...... nkey hematopoietic stem cells.
@nl
P2093
P2860
P356
P1476
Development of a high-titer re ...... nkey hematopoietic stem cells.
@en
P2093
Agricola B
McDonagh KT
Nienhuis AW
P2860
P304
P356
10.1073/PNAS.87.10.3738
P407
P4510
P577
1990-05-01T00:00:00Z