A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. - Wikidata - awgldk - TriplyDB

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity.

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity.

http://www.wikidata.org/entity/Q33660588

about

Migration of Th1 lymphocytes is regulated by CD152 (CTLA-4)-mediated signaling via PI3 kinase-dependent Akt activation Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis Par1b/MARK2 phosphorylates kinesin-like motor protein GAKIN/KIF13B to regulate axon formation Role of RacC for the regulation of WASP and phosphatidylinositol 3-kinase during chemotaxis of Dictyostelium Podocalyxin EBP50 ezrin molecular complex enhances the metastatic potential of renal cell carcinoma through recruiting Rac1 guanine nucleotide exchange factor ARHGEF7 A molecular model for axon guidance based on cross talk between rho GTPases.A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling.Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes Phosphoinositides: tiny lipids with giant impact on cell regulation Leukocyte migration from a fish eye's view Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration p21-Activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophils Novel protein Callipygian defines the back of migrating cells.Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour Multiple phosphatidylinositol 3-kinases regulate vaccinia virus morphogenesis Rac1-dependent lamellipodial motility in prostate cancer PC-3 cells revealed by optogenetic control of Rac1 activity How cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motility Oscillatory behavior of neutrophils under opposing chemoattractant gradients supports a winner-take-all mechanism A mathematical model for neutrophil gradient sensing and polarization Gβ Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration LOVTRAP: an optogenetic system for photoinduced protein dissociation Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae.Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cells Treponema denticola major outer sheath protein impairs the cellular phosphoinositide balance that regulates neutrophil chemotaxis Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.Regulation of the desensitization and ion selectivity of ATP-gated P2X2 channels by phosphoinositides An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells Alterations in cytoskeletal and immune function-related proteome profiles in whole rat lung following intratracheal instillation of heparin LIMK1 regulates Golgi dynamics, traffic of Golgi-derived vesicles, and process extension in primary cultured neurons Erythrocyte scaffolding protein p55/MPP1 functions as an essential regulator of neutrophil polarity.Laminin alpha5 is required for dental epithelium growth and polarity and the development of tooth bud and shape NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane.Role of phosphoinositide 3-kinase regulatory isoforms in development and actin rearrangement Signaling networks that regulate cell migration

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P2860

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity.

http://www.wikidata.org/entity/Q33660588

description

2002 nî lūn-bûn

@nan

2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հուլիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

A PtdInsP(3)- and Rho GTPase-m ...... regulates neutrophil polarity.

@ast

A PtdInsP(3)- and Rho GTPase-m ...... regulates neutrophil polarity.

@en

type

label

A PtdInsP(3)- and Rho GTPase-m ...... regulates neutrophil polarity.

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A PtdInsP(3)- and Rho GTPase-m ...... regulates neutrophil polarity.

@en

prefLabel

A PtdInsP(3)- and Rho GTPase-m ...... regulates neutrophil polarity.

@ast

A PtdInsP(3)- and Rho GTPase-m ...... regulates neutrophil polarity.

@en

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Nature Cell Biology

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A PtdInsP(3)- and Rho GTPase-m ...... regulates neutrophil polarity.

@en

P2093

Glenn D Prestwich

http://www.w3.org/2001/XMLSchema#string

Henry R Bourne

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Marc W Kirschner

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Orion D Weiner

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Paul O Neilsen

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P2860

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells

Rac GTPase interacts specifically with phosphatidylinositol 3-kinase

Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

Spatial sensing in fibroblasts mediated by 3' phosphoinositides.

Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis.

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

Spatial control of actin polymerization during neutrophil chemotaxis.

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10.1038/NCB811

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7

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4

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Lewis C. Cantley

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2002-07-01T00:00:00Z

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11295477

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1050217513

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12080346

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2823287

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