Role of phosphoinositide 3-kinase regulatory isoforms in development and actin rearrangement
about
The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complexAbi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cellsPhosphoinositides: tiny lipids with giant impact on cell regulationMultiple phosphatidylinositol 3-kinases regulate vaccinia virus morphogenesisGenetic insights into the mechanisms of Fgf signalingPI3K/PTEN signaling in angiogenesis and tumorigenesisLRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activationPI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathwaysPhosphoinositide 3-kinase p85beta regulates invadopodium formation.PI3K activation is required for PMA-directed activation of cSrc by AFAP-110.Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms.Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.RNAi screen of endoplasmic reticulum-associated host factors reveals a role for IRE1alpha in supporting Brucella replication.Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinaseClass IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy.p85beta phosphoinositide 3-kinase regulates CD28 coreceptor functionMicroglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicityOncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)Downregulation of PI3Kcb utilizing adenovirus-mediated transfer of siRNA attenuates bone cancer pain.Identification of mutations in distinct regions of p85 alpha in urothelial cancer.Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase.AKT phosphorylation is essential for insulin-induced relaxation of rat vascular smooth muscle cellsT-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling.Simvastatin inhibits Staphylococcus aureus host cell invasion through modulation of isoprenoid intermediates.The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance.PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiationp85β phosphoinositide 3-kinase subunit regulates tumor progressionReelin signals through phosphatidylinositol 3-kinase and Akt to control cortical development and through mTor to regulate dendritic growth.Class 1A PI3K regulates vessel integrity during development and tumorigenesis.Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cellsActivation of T cells by cross-linking Qa-2, the ped gene product, requires Fyn.Many roads lead to oncogene-induced senescence.Myristoylated p110α Causes Embryonic Death Due to Developmental and Vascular Defects.cAMP-GEF cytoprotection by Src tyrosine kinase activation of phosphoinositide-3-kinase p110 beta/alpha in rat hepatocytesOncogene-induced senescence: an essential role for Runx.PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRαBeta interferon regulation of glucose metabolism is PI3K/Akt dependent and important for antiviral activity against coxsackievirus B3.The regulation of tumor-suppressive microRNA, miR-126, in chronic lymphocytic leukemia.Is prenatal myo-inositol deficiency a mechanism of CNS injury in galactosemia?Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit.
P2860
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P2860
Role of phosphoinositide 3-kinase regulatory isoforms in development and actin rearrangement
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Role of phosphoinositide 3-kin ...... opment and actin rearrangement
@ast
Role of phosphoinositide 3-kin ...... opment and actin rearrangement
@en
type
label
Role of phosphoinositide 3-kin ...... opment and actin rearrangement
@ast
Role of phosphoinositide 3-kin ...... opment and actin rearrangement
@en
prefLabel
Role of phosphoinositide 3-kin ...... opment and actin rearrangement
@ast
Role of phosphoinositide 3-kin ...... opment and actin rearrangement
@en
P2093
P2860
P1476
Role of phosphoinositide 3-kin ...... opment and actin rearrangement
@en
P2093
Claudine M Yballe
David A Fruman
Jonathan A Deane
Lewis C Cantley
Saskia M Brachmann
Sheila M Thomas
P2860
P304
P356
10.1128/MCB.25.7.2593-2606.2005
P407
P577
2005-04-01T00:00:00Z