Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine. - Wikidata - awgldk - TriplyDB

Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

http://www.wikidata.org/entity/Q33680168

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Epigenetic modifications and diabetic retinopathy A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation Brain feminization requires active repression of masculinization via DNA methylation Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay DNA methylation mediates the discriminatory power of associative long-term memory in honeybees Reversibility of membrane N-glycome of HeLa cells upon treatment with epigenetic inhibitors.3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models.Azacitidine in the management of patients with myelodysplastic syndromes.Development of a universal radioactive DNA methyltransferase inhibition test for high-throughput screening and mechanistic studies Zebularine partially reverses GST methylation in prostate cancer cells and restores sensitivity to the DNA minor groove binder brostallicin.Manipulating the epigenome for the treatment of urological malignancies.The application of delivery systems for DNA methyltransferase inhibitors.Epigenetic drug discovery: targeting DNA methyltransferases.Epigenetic-based therapies in cancer: progress to date.The emerging role of DNA methylation in epileptogenesis.Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies.DNA methyl transferase 1: regulatory mechanisms and implications in health and disease.DNA Hypomethylating Drugs in Cancer Therapy.DNA Methyltransferase Inhibitors: Development and Applications.Epimutations mimic genomic mutations of DNMT3A in acute myeloid leukemia.2´-deoxy-5,6-dihydro-5-azacytidine - a less toxic alternative of 2´-deoxy-5-azacytidine: a comparative study of hypomethylating potential.Hematopoietic stem and progenitor cells acquire distinct DNA-hypermethylation during in vitro culture.Repair of DNA Damage Induced by the Cytidine Analog Zebularine Requires ATR and ATM in Arabidopsis.DNA Methylation Inhibitor Zebularine Confers Stroke Protection in Ischemic Rats.Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models.Circadian behavior is light-reprogrammed by plastic DNA methylation.Targeting DNA Methyltranferases in Urological Tumors.The Methylation Status of the Epigenome: Its Emerging Role in the Regulation of Tumor Angiogenesis and Tumor Growth, and Potential for Drug Targeting

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Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

http://www.wikidata.org/entity/Q33680168

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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name

Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

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Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

@en

type

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Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

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Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

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prefLabel

Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

@ast

Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

@en

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JOURNAL.PONE.0012388

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Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

@en

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Anne-Laure Guieysse-Peugeot

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Catherine Sénamaud-Beaufort

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Christine Champion

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Loïc Ponger

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Paola B Arimondo

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Renata Z Jurkowska

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P2860

Zebularine: A Novel DNA Methylation Inhibitor that Forms a Covalent Complex with DNA Methyltransferases

The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing

Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes

DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution

Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases

Molecular enzymology of mammalian DNA methyltransferases

Epigenetics in human disease and prospects for epigenetic therapy

DNA methylation: past, present and future directions.

Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry.

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8

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Dominique Guianvarc'h

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2010-08-24T00:00:00Z

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46108526

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