A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A.
about
Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSAAntigenic variation in Plasmodium falciparum: gene organization and regulation of the var multigene familyTranscriptome analysis of antigenic variation in Plasmodium falciparum--var silencing is not dependent on antisense RNAMutually exclusive expression of virulence genes by malaria parasites is regulated independently of antigen production.Malaria: progress, perils, and prospects for eradicationThe Structure of a Chondroitin Sulfate-binding Domain Important in Placental MalariaStructure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate AStructural Comparison of Two CSPG-Binding DBL Domains from the VAR2CSA Protein Important in Malaria during PregnancyA novel protein kinase family in Plasmodium falciparum is differentially transcribed and secreted to various cellular compartments of the host cellDiscovery of a novel and conserved Plasmodium falciparum exported protein that is important for adhesion of PfEMP1 at the surface of infected erythrocytesModeling cytoadhesion of Plasmodium falciparum-infected erythrocytes and leukocytes-common principles and distinctive featuresMalarial parasite diversity in chimpanzees: the value of comparative approaches to ascertain the evolution of Plasmodium falciparum antigensVar2CSA minimal CSA binding region is located within the N-terminal regionIdentification of a role for the PfEMP1 semi-conserved head structure in protein trafficking to the surface of Plasmodium falciparum infected red blood cells.Identification of malaria parasite-infected red blood cell surface aptamers by inertial microfluidic SELEX (I-SELEX).Clag9 is not essential for PfEMP1 surface expression in non-cytoadherent Plasmodium falciparum parasites with a chromosome 9 deletion.Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration.Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates.Dissection of the role of PfEMP1 and ICAM-1 in the sensing of Plasmodium-falciparum-infected erythrocytes by natural killer cellsDisruption of var2csa gene impairs placental malaria associated adhesion phenotype.Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression.Default Pathway of var2csa switching and translational repression in Plasmodium falciparumIdentification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSAAn upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria.Differential recognition of P. falciparum VAR2CSA domains by naturally acquired antibodies in pregnant women from a malaria endemic area.Towards the rational design of a candidate vaccine against pregnancy associated malaria: conserved sequences of the DBL6epsilon domain of VAR2CSA.Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies.Plasmodium falciparum FIKK kinase members target distinct components of the erythrocyte membrane.Heterozygous HbAC but not HbAS is associated with higher newborn birthweight among women with pregnancy-associated malaria.Strain-transcendent immune response to recombinant Var2CSA DBL5-ε domain block P. falciparum adhesion to placenta-derived BeWo cells under flow conditions.Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.Dynamics in the cytoadherence phenotypes of Plasmodium falciparum infected erythrocytes isolated during pregnancy.Histopathologies, immunolocalization, and a glycan binding screen provide insights into Plasmodium falciparum interactions with the human placenta.Allelic diversity of the Plasmodium falciparum erythrocyte membrane protein 1 entails variant-specific red cell surface epitopes.Antibodies to a full-length VAR2CSA immunogen are broadly strain-transcendent but do not cross-inhibit different placental-type parasite isolatesEvaluation of the antigenic diversity of placenta-binding Plasmodium falciparum variants and the antibody repertoire among pregnant women.Immunization with VAR2CSA-DBL5 recombinant protein elicits broadly cross-reactive antibodies to placental Plasmodium falciparum-infected erythrocytes.Investigating the host binding signature on the Plasmodium falciparum PfEMP1 protein family.CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparumFrom in vivo to in vitro: dynamic analysis of Plasmodium falciparum var gene expression patterns of patient isolates during adaptation to culture.
P2860
Q24620671-9C3A8251-B656-4C50-AC81-7D1FA0161467Q24672872-EDF00834-A1C7-47A5-8CD2-AE3C67DD5444Q24813703-4B47DCD9-BCCD-4850-8FA2-7F38B0B53EA6Q25257163-E88F077F-3516-40D0-90EE-C856C7749BE8Q27485634-74A98F0D-E96F-46EB-83EE-52B01AAAE921Q27650818-76B297C8-7549-4A37-9E80-BD9B194BACD5Q27653526-4B3CB85C-F898-4165-95A6-AC1D2252103AQ27657099-135DCE48-E9C2-420D-A09E-5A8278DF6680Q27972747-0F58D610-0D3C-42CA-8694-5EE7C9A731AFQ27974160-A4F8C5C5-3BE1-417F-A429-65067768D474Q28071399-12F8831B-BBFA-4F10-B476-2974B5E55BCEQ28661352-3E5896C0-BD0A-47FE-B9DE-1081D4BE5BCBQ28744428-784D87C5-1739-4423-850A-FD36AE2BDC29Q30496607-26032C9C-087E-4D0D-8103-C64A774401B8Q30656207-540581CD-8421-4D37-8FE1-BE8C8FEBBAF1Q31044131-2C063E4D-ABD8-40AD-BE7D-309EF78E33F1Q33263953-E2372305-8010-4735-943D-0CB3482C81F9Q33272663-97E44224-CBBF-4A41-8D0C-65BDBDE7FA1BQ33274651-72FAAE92-1B59-4E98-99E2-248EC2A342B0Q33299476-D2F3A06B-BA95-4A3D-ABF3-035199F4D64EQ33325481-19F3A568-9ECD-4E94-B2CA-27895E73086DQ33330268-85141811-AA9D-425E-B5B8-9319C0A82A71Q33340867-91F00466-7F7A-4107-98B8-91CC1B9F86D3Q33396980-95D07A64-7C42-43FB-B232-0CAE70D3AEC8Q33532592-6FCCEA26-5EA3-420D-80F2-B79A760A49BCQ33619319-D6A66E76-0ECE-4233-8B04-973C0F2F0500Q33634689-80333F4C-9CF9-4F6C-8638-864D25159BDDQ33644304-10A7EAFE-A461-4316-BEF9-05DB1A21964CQ33684063-B62CE0B4-5C44-4B76-85F6-AA39CFC287B4Q33691325-B8606C4B-ABF2-4A89-9E57-2550424FC407Q33700519-C32F4E0C-564E-4324-B307-DE8917A297DDQ33721310-4B686A2F-0D88-498F-9043-65191C13E02FQ33806360-4C8B83E9-7046-48E8-960F-626AEE37F737Q33813188-B49A4A68-CB86-46F9-908E-C2C44C68D000Q33822296-0BA39449-50BC-4E2B-A16B-922B7B559054Q33826049-1E294001-38DF-431B-8A52-9031A4E22A8DQ33826076-5FCDF31E-E645-489D-B12F-B1010B5CFE00Q33900642-1413B08A-A1CF-4A7D-AF57-7B44835A3696Q33911270-82B73A09-97D7-42FC-8D0D-53873062EE12Q33932976-7ADD8752-2ABB-4225-8172-24E2022F137E
P2860
A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A single member of the Plasmod ...... ceptor chondroitin sulphate A.
@ast
A single member of the Plasmod ...... ceptor chondroitin sulphate A.
@en
A single member of the Plasmod ...... ceptor chondroitin sulphate A.
@nl
type
label
A single member of the Plasmod ...... ceptor chondroitin sulphate A.
@ast
A single member of the Plasmod ...... ceptor chondroitin sulphate A.
@en
A single member of the Plasmod ...... ceptor chondroitin sulphate A.
@nl
prefLabel
A single member of the Plasmod ...... ceptor chondroitin sulphate A.
@ast
A single member of the Plasmod ...... ceptor chondroitin sulphate A.
@en
A single member of the Plasmod ...... ceptor chondroitin sulphate A.
@nl
P2093
P2860
P356
P1433
P1476
A single member of the Plasmod ...... ceptor chondroitin sulphate A.
@en
P2093
Artur Scherf
Benoit Gamain
Catherine Lépolard
Christine Scheidig
Jude Przyborski
Jürg Gysin
Nicola K Viebig
P2860
P304
P356
10.1038/SJ.EMBOR.7400466
P577
2005-08-01T00:00:00Z